The Genetic Architecture of Major Depressive Disorder in Han Chinese Women
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2016.3578
Abstract: Importance Despite the moderate, well-demonstrated heritability of major depressive disorder (MDD), there has been limited success in identifying replicable genetic risk loci, suggesting a complex genetic architecture. Research is needed to quantify the relative contribution… read more here.
Keywords: risk; etiology; mdd; genetic architecture ... See more keywords
Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25421
Abstract: Sickle cell disease (SCD) is the most common monogenic disorder in the world. Notably, there is extensive clinical heterogeneity in SCD that cannot be fully accounted for by known factors, and in particular, the extent… read more here.
Keywords: family; cohort; cell disease; heritability ... See more keywords
Heritability in the Rhesus Macaque (Macaca mulatta) Vertebral Column
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Primatology"
DOI: 10.1002/ajp.23686
Abstract: The vertebral column plays a central role in primate locomotion and positional behavior. Understanding its evolution, therefore, has the potential to clarify evolutionary processes that have occurred in the primate lineage as well as the… read more here.
Keywords: vertebral column; macaca mulatta; thoracic; heritability ... See more keywords
Heritability and genetic integration of tooth size in the South Carolina Gullah.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.23290
Abstract: OBJECTIVES This article provides estimates of narrow-sense heritability and genetic pleiotropy for mesiodistal tooth dimensions for a sample of 20th century African American individuals. Results inform biological distance analysis and offer insights into patterns of… read more here.
Keywords: narrow sense; genetic integration; integration; sense heritability ... See more keywords
The Familial Risk of Autism Spectrum Disorder with and without Intellectual Disability
Sign Up to like & getrecommendations! Published in 2020 at "Autism Research"
DOI: 10.1002/aur.2417
Abstract: Autism spectrum disorder (ASD) is highly heritable, yet how its familial risk and heritability may vary by cognitive ability is not well understood. In this population‐based cohort study, we examined the familial risk and heritability… read more here.
Keywords: risk; asd asd; familial risk; asd ... See more keywords
Heritability of social behavioral phenotypes and preliminary associations with autism spectrum disorder risk genes in rhesus macaques: A whole exome sequencing study
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2675
Abstract: Nonhuman primates and especially rhesus macaques (Macaca mulatta) have been indispensable animal models for studies of various aspects of neurobiology, developmental psychology, and other aspects of neuroscience. While remarkable progress has been made in our… read more here.
Keywords: heritability; autism; social behavior; rhesus macaques ... See more keywords
SNP‐based heritability and selection analyses: Improved models and new results
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202100170
Abstract: Complex‐trait genetics has advanced dramatically through methods to estimate the heritability tagged by SNPs, both genome‐wide and in genomic regions of interest such as those defined by functional annotations. The models underlying many of these… read more here.
Keywords: based heritability; heritability; heritability selection; snp based ... See more keywords
Heritability of floral traits in Allium cepa L. populations from biparental crosses
Sign Up to like & getrecommendations! Published in 2024 at "Crop Science"
DOI: 10.1002/csc2.21204
Abstract: Onions (Allium cepa L.) are one of the main vegetable crops worldwide. As an allogamous species with entomophilous pollination, floral traits play a critical role in seed production. Improving seed yield, especially for hybrid seed… read more here.
Keywords: seed; heritability; allium cepa; seed production ... See more keywords
Heritability, heterosis, and hybrid/inbred classification ability of maize leaf hyperspectral signals under changing soil nitrogen
Sign Up to like & getrecommendations! Published in 2025 at "Crop Science"
DOI: 10.1002/csc2.70073
Abstract: This study investigates the use of leaf hyperspectral data to understand genetic and environmental influences on maize (Zea mays L.) leaf reflectance and its implications for genetic analysis. The Backcrossed Germplasm Enhancement of Maize (BGEM)… read more here.
Keywords: classification; heterosis; nitrogen; heritability ... See more keywords
Heritability of dispersal‐related larval traits in the clown anemonefish Amphiprion percula
Sign Up to like & getrecommendations! Published in 2022 at "Ecology and Evolution"
DOI: 10.1002/ece3.9541
Abstract: Abstract A major goal of marine ecology is to identify the drivers of variation in larval dispersal. Larval traits are emerging as an important potential source of variation in dispersal outcomes, but little is known… read more here.
Keywords: dispersal; ecology; heritability; larval traits ... See more keywords
Summary statistic analyses can mistake confounding bias for heritability
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22259
Abstract: Linkage disequilibrium SCore regression (LDSC) has become a popular approach to estimate confounding bias, heritability, and genetic correlation using only genome‐wide association study (GWAS) test statistics. SumHer is a newly introduced alternative with similar aims.… read more here.
Keywords: summary statistic; confounding bias; bias heritability; statistic analyses ... See more keywords