Simultaneous estimation of bi-directional causal effects and heritable confounding from GWAS summary statistics
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DOI: 10.1038/s41467-021-26970-w
Abstract: Mendelian Randomisation (MR) is an increasingly popular approach that estimates the causal effect of risk factors on complex human traits. While it has seen several extensions that relax its basic assumptions, most suffer from two… read more here.
Keywords: simultaneous estimation; summary statistics; heritable confounder; causal effects ... See more keywords