Glutamatergic Projections from the Entorhinal Cortex to Dorsal Dentate Gyrus Mediate Context-Induced Reinstatement of Heroin Seeking
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychopharmacology"
DOI: 10.1038/npp.2017.14
Abstract: Reexposure to the context associated with heroin intake provokes relapse to drug taking after abstinence. The dorsal dentate gyrus (dDG) and entorhinal cortex (EC) have been implicated in contextual memory processing, but the underlying circuit… read more here.
Keywords: context; reinstatement heroin; heroin seeking; context induced ... See more keywords
The role of the paraventricular nucleus of the thalamus in the augmentation of heroin seeking induced by chronic food restriction
Sign Up to like & getrecommendations! Published in 2019 at "Addiction Biology"
DOI: 10.1111/adb.12708
Abstract: Drug addiction is a chronic disorder that is characterized by compulsive drug seeking and involves cycling between periods of compulsive drug use, abstinence, and relapse. In both human addicts and animal models of addiction, chronic… read more here.
Keywords: chronic food; food restriction; food; heroin seeking ... See more keywords
Cognitive Enhancer Donepezil Attenuates Heroin-Seeking Behavior Induced by Cues in Rats.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2203076
Abstract: PURPOSE Opioid use disorder is a significant global problem. Chronic heroin use is associated with impairment of cognitive function and conscious control ability. The cholinergic system can be disrupted following heroin administration, indicating that activation… read more here.
Keywords: administration; heroin; induced cues; heroin seeking ... See more keywords