HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26647
Abstract: Human endogenous retroviruses (HERVs) represent 8% of the human genome. The expression of HERVs and their immune impact have not been extensively studied in Acute Myeloid Leukemia (AML). In this study, we used a reference… read more here.
Keywords: leukemia stem; source; hervs; stem cells ... See more keywords
The role of human endogenous retroviruses in gliomas: from etiological perspectives and therapeutic implications.
Sign Up to like & getrecommendations! Published in 2021 at "Neuro-oncology"
DOI: 10.1093/neuonc/noab142
Abstract: Accounting for approximately 8% of the human genome, Human Endogenous Retroviruses (HERVs) have been implicated in a variety of cancers including gliomas. In normal cells, tight epigenetic regulation of HERVs prevent aberrant expression; however, in… read more here.
Keywords: hervs; human endogenous; endogenous retroviruses; anti tumor ... See more keywords
Modulation of HERV Expression by Four Different Encephalitic Arboviruses during Infection of Human Primary Astrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112505
Abstract: Human retroelements (HERVs) are retroviral origin sequences fixed in the human genome. HERVs induction is associated with neurogenesis, cellular development, immune activation, and neurological disorders. Arboviruses are often associated with the development of encephalitis. The… read more here.
Keywords: modulation; primary astrocytes; hervs; modulation herv ... See more keywords