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Hes1 Knockdown Exacerbates Ischemic Stroke Following tMCAO by Increasing ER Stress-Dependent Apoptosis via the PERK/eIF2α/ATF4/CHOP Signaling Pathway

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1 Published in 2019 at "Neuroscience Bulletin"

DOI: 10.1007/s12264-019-00411-7

Abstract: Apoptosis induced by endoplasmic reticulum (ER) stress plays a crucial role in mediating brain damage after ischemic stroke. Recently, Hes1 (hairy and enhancer of split 1) has been implicated in the regulation of ER stress,… read more here.

Keywords: eif2 atf4; ischemic stroke; apoptosis; perk eif2 ... See more keywords