Notch1/Hes1-PTEN/AKT/IL-17A feedback loop regulates Th17 cell differentiation in mouse psoriasis-like skin inflammation
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DOI: 10.3892/mmr.2022.12739
Abstract: IL-17A, the effector cytokine of T helper (Th) 17 cells, plays a crucial role in the pathogenesis of psoriasis. The Notch1 and PI3K/AKT signaling pathways are implicated in Th17 cell differentiation and IL-17A production. The… read more here.
Keywords: pten akt; hes1; 17a feedback; hes1 pten ... See more keywords