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   Articles with "hesc" as a keyword



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Active compounds present inRosmarinus officinalis leaves andScutellaria baicalensis root evaluated as new therapeutic agents for endometriosis.

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recommendations! Published in 2018 at "Reproductive biomedicine online"

DOI: 10.1016/j.rbmo.2018.09.018

Abstract: RESEARCH QUESTION Can carnosic acid, (CA) rosmarinic acid (RA) and wogonin (WG) inhibit the growth of cultured human endometrial stromal cells and endometriotic-like lesions induced in a BALB/c model of endometriosis? DESIGN Primary stromal cell… read more here.

Keywords: hesc; active compounds; day day; compounds present ... See more keywords

Whole-genome analysis of human embryonic stem cells enables rational line selection based on genetic variation

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recommendations! Published in 2022 at "Cell Stem Cell"

DOI: 10.1016/j.stem.2022.01.011

Abstract: Summary Despite their widespread use in research, there has not yet been a systematic genomic analysis of human embryonic stem cell (hESC) lines at a single-nucleotide resolution. We therefore performed whole-genome sequencing (WGS) of 143… read more here.

Keywords: human embryonic; analysis human; stem; hesc ... See more keywords

Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?

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recommendations! Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-21949-z

Abstract: A key issue in the development of atrial-selective antiarrhythmic drugs is the limited access to human heart tissue. Goldfracht et al. have used atrialand ventricular-differentiated human embryonic stem cell‐derived cardiomyocytes (hESC-CMs) to dissect chamber-selective actions… read more here.

Keywords: stem cell; hesc; derived cardiomyocytes; cell derived ... See more keywords

Effect of exposure to ionizing radiation on competitive proliferation and differentiation of hESC

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recommendations! Published in 2022 at "International Journal of Radiation Biology"

DOI: 10.1080/09553002.2023.2146231

Abstract: Abstract Purpose We studied the effects of computed tomography (CT) scan irradiation on proliferation and differentiation of human embryonic stem cells (hESCs). It was reported that hESC is extremely radiosensitive; exposure of hESC in cultures… read more here.

Keywords: h9gfp; hesc; radiation; differentiation ... See more keywords

Fabrication of vascularized tissue constructs under chemically defined culture conditions.

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recommendations! Published in 2020 at "Biofabrication"

DOI: 10.1088/1758-5090/aba0c2

Abstract: Three-dimensional (3D) biofabrication techniques that enable the production of multicellular tissue equivalents for applications in basic biology, drug screening and regenerative medicne. Fabrication of these tissue constructs with in-built microvasculature enables recapitulation of the biological… read more here.

Keywords: hesc; fabrication vascularized; tissue; culture ... See more keywords

Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes

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recommendations! Published in 2022 at "Cardiovascular Research"

DOI: 10.1093/cvr/cvac065

Abstract: Abstract Aims The apelin receptor, a G protein-coupled receptor, has emerged as a key regulator of cardiovascular development, physiology, and disease. However, there is a lack of suitable human in vitro models to investigate the… read more here.

Keywords: receptor knockdown; apelin receptor; hesc; heart ... See more keywords

Enhanced quality of hESC‐derived melanocytes through modified concentration of endothelin‐1

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recommendations! Published in 2024 at "Experimental Dermatology"

DOI: 10.1111/exd.15004

Abstract: The study investigated the effectiveness of EDN1 and EDN3 cytokines in the differentiation of melanocytes from hESCs. The findings showed that 100 nM EDN1 was more effective in promoting hESC to CD117+/TYR+ melanoblasts compared to 100 nM… read more here.

Keywords: quality hesc; stage; enhanced quality; derived melanocytes ... See more keywords

Retinoid Signaling Controlled by SRC-2 in Decidualization Revealed by Transcriptomics.

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recommendations! Published in 2018 at "Reproduction"

DOI: 10.1530/rep-18-0282

Abstract: Establishment of a successful pregnancy requires not only implantation of a healthy embryo into a receptive uterus but also progesterone receptor (PGR)-dependent transformation of endometrial stromal cells (ESCs) into specialized decidual cells. Decidual cells support… read more here.

Keywords: hesc; controlled src; retinoid signaling; signaling controlled ... See more keywords