Functional assessment of cryopreserved clinical grade hESC-RPE cells as a qualified cell source for stem cell therapy of retinal degenerative diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108305
Abstract: The biosafety and efficiency of transplanting retinal pigment epithelial (RPE) cells derived from both human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have been evaluated in phase I and phase II clinical… read more here.
Keywords: hesc rpe; rpe cells; cryopreserved hesc; stem ... See more keywords
Comparative proteomic analysis of human embryonic stem cell-derived and primary human retinal pigment epithelium
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DOI: 10.1038/s41598-017-06233-9
Abstract: Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) provide an unlimited cell source for retinal cell replacement therapies. Clinical trials using hESC-RPE to treat diseases such as age-related macular degeneration (AMD) are currently underway.… read more here.
Keywords: hesc rpe; embryonic stem; cell; human embryonic ... See more keywords
Denuded Descemet’s membrane supports human embryonic stem cell-derived retinal pigment epithelial cell culture
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281404
Abstract: Recent clinical studies suggest that retinal pigment epithelial (RPE) cell replacement therapy may preserve vision in retinal degenerative diseases. Scaffold-based methods are being tested in ongoing clinical trials for delivering pluripotent-derived RPE cells to the… read more here.
Keywords: culture; cell; rpe cells; rpe ... See more keywords