LncRNA MALAT1 promotes decidualization of endometrial stromal cells via sponging miR‐498‐3p and targeting histone deacetylase 4
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11814
Abstract: Decidualization of human endometrial stromal cells (hESCs) is important for the maintenance of a successful pregnancy. Histone deacetylase 4 (HDAC4) was reported to be involved in the dysfunction of decidua‐derived mesenchymal stem cells. However, the… read more here.
Keywords: mir 498; endometrial stromal; hescs; hdac4 ... See more keywords
Straight to the X: Modeling Human X Chromosome Inactivation in hESCs by FGF Signal Blockade.
Sign Up to like & getrecommendations! Published in 2020 at "Cell stem cell"
DOI: 10.1016/j.stem.2020.08.008
Abstract: In this issue of Cell Stem Cell, An et al. (2020) provide a model to study human X chromosome inactivation. They followed X chromosome activity and traced cellular heterogeneity in naive hESCS, showed that it is… read more here.
Keywords: blockade; chromosome inactivation; hescs; human chromosome ... See more keywords
Melatonin regulates proliferation and apoptosis of endometrial stromal cells via MT1.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmab108
Abstract: Endometrial dysfunction is an important factor for implantation failure. The function of the endometrium is regulated by multiple factors like sex hormones and circadian rhythms. Endometrial stromal cells (ESCs) are a major cellular component in… read more here.
Keywords: apoptosis; proliferation apoptosis; stromal cells; endometrial stromal ... See more keywords
Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13471
Abstract: Robust allogeneic immune reactions after transplantation impede the translational pace of human embryonic stem cells (hESCs)‐based therapies. Selective genetic editing of human leucocyte antigen (HLA) molecules has been proposed to generate hESCs with immunocompatibility, which,… read more here.
Keywords: hla; hescs; immunocompatible hesc; line ... See more keywords
miR-6087 Might Regulate Cell Cycle–Related mRNAs During Cardiomyogenesis of hESCs
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics and Biology Insights"
DOI: 10.1177/11779322231161918
Abstract: MicroRNAs (miRNAs) are small noncoding RNAs that act as negative regulators of gene expression at the post-transcriptional level, promoting mRNA degradation or translation repression. Despite the well-described presence of miRNAs in various human tissues, there… read more here.
Keywords: cell cycle; hescs; mir 6087; mir ... See more keywords
Glucose and lipid metabolisms in human endometrial stromal cells during decidualization.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine journal"
DOI: 10.1507/endocrj.ej23-0099
Abstract: Decidualization is a process of differentiation of human endometrial stromal cells (hESCs) accompanied by dramatic changes in cellular functions. This process is critical for embryo implantation and the establishment of pregnancy. Impairment of decidualization of… read more here.
Keywords: endometrial stromal; decidualization; human endometrial; hescs ... See more keywords