Hesperidin loaded bilosomes mitigate the nephrotoxicity induced by methotrexate; biochemical and molecular in vivo investigations
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DOI: 10.1186/s12882-025-04328-4
Abstract: Drugs, chemicals, and poisons may damage kidneys and cause chronic renal disease. About 20% of community and hospital acute renal failures are drug-related. Hesperidin-loaded bilosomes (HES-BS) nanoformula was tested for nephroprotection against methotrexate (MTX)-induced kidney… read more here.
Keywords: bilosomes mitigate; gene expression; hesperidin loaded; hes nanoformula ... See more keywords
Amelioration of Full-Thickness Wound Using Hesperidin Loaded Dendrimer-Based Hydrogel Bandages
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DOI: 10.3390/bios12070462
Abstract: Wound healing is a complex biological phenomenon, having different but overlapping stages to obtained complete re-epithelization. The aim of the current study was to develop a dendrimer-based hydrogel bandage, to ameliorate full-thickness wounds. Hesperidin, a… read more here.
Keywords: dendrimer; dendrimer based; hesperidin loaded; full thickness ... See more keywords
Hesperidin-Loaded Lipid Polymer Hybrid Nanoparticles for Topical Delivery of Bioactive Drugs
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DOI: 10.3390/ph15020211
Abstract: Hesperidin is a bioflavonoid constituent that among many other biological activities shows significant wound healing properties. However, the bioavailability of hesperidin when applied topically is limited due to its low solubility and systemic absorption, so… read more here.
Keywords: hesperidin loaded; lipid polymer; hybrid; polymer hybrid ... See more keywords