Synthesis of 4-aryl(hetaryl)pyrazolo[1,5-a]pyrazines by palladium-catalyzed Suzuki–Miyaura cross coupling
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02579-2
Abstract: 4-Bromopyrazolo[1,5-a]pyrazines react with aryl(hetaryl)boronic acids in the presence of catalytic amounts of Pd(dppf)Cl2·CH2Cl2 and an excess of Cs2CO3 in the MeCN–H2O, 9:1 solvent system with the formation of 4-aryl(hetaryl)pyrazolo[1,5-a]pyrazines. read more here.
Keywords: pyrazolo pyrazines; hetaryl pyrazolo; aryl hetaryl; synthesis aryl ... See more keywords
The unusual influence of hetaryl groups on the direct conversion of some secondary alcohols into thiols with Lawesson’s reagent: elucidation of the reaction mechanism
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Sulfur Chemistry"
DOI: 10.1080/17415993.2017.1313257
Abstract: ABSTRACT A series of hetaryl-substituted methanols were used for direct conversion into the corresponding thiols by treatment with Lawesson’s reagent in boiling toluene. Unexpectedly, the respective sulfides were formed exclusively. In the case of chiral… read more here.
Keywords: lawesson reagent; direct conversion; influence hetaryl; unusual influence ... See more keywords
Synthesis and Structure of Hetaryl Substituted 2,5-dioxo-1,2,3,4,5,6,7,8- Octahydroquinolines.
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DOI: 10.2174/1570179419666220406233307
Abstract: AIMS AND OBJECTIVE Condensation of 5-hetarylidene-2,2-dimethyl-1,3-dioxane-4,6-diones with 5,5-dimethyl-3-arylamino-2-cyclohexanones yields 1-aryl-4-hetaryl-7,7-dimethyl-2,5-dioxo-l,2,3,4,5,5,7,8-octahydro-quinolines. The structures of all the synthesized compounds have been verified by IR, 1H-NMR, 13C-NMR, and mass spectral methods. The 13C-NMR assignments were supported by HSQC… read more here.
Keywords: synthesis structure; hetaryl; structure hetaryl; mass ... See more keywords