Quantitative Single Cell Analysis for Transcriptional Activity of p53 Hetero-tetramers between Wild-type Protein and Oligomerization Domain
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DOI: 10.1246/cl.170980
Abstract: p53 acts as a transcriptional factor for tumor suppression via tetramerization. Although the dominant-negative effect occurs by hetero-oligomerization between wild-type and mutant p53, the precise mechanism remains unclear. Here, we report an analysis of the… read more here.
Keywords: hetero tetramers; analysis transcriptional; oligomerization; p53 ... See more keywords