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Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c01053
Abstract: Phenethyltriflamides react with 1,3-dienes upon treatment with a catalytic amount of Pd(OAc)2 and Cu(OAc)2/O2 as oxidant to afford chemo-, regio- and diastereoselectively 2,3,4,5-tetrahydro-1H-benzo[d]azepines (3-benzazepine derivatives) in good to excellent yields. A DFT study of the…
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Keywords:
heteroannulation phenethylamides;
dienes dopaminergic;
heteroannulation;
palladium catalyzed ... See more keywords