Synthesis and evaluation of N-heteroaromatic ring-based analogs of piperlongumine as potent anticancer agents.
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DOI: 10.1016/j.ejmech.2017.06.046
Abstract: Piperlongumine (PL) selectively targets a wide spectrum of cancer cells and induces their death by triggering various pathways, including apoptosis, necrosis and autophagy. However, the poor solubility is a serious concern for intensive study and… read more here.
Keywords: heteroaromatic ring; based analogs; potent anticancer; ring ... See more keywords