Design, synthesis and in vitro antiproliferation activity of some 2-aryl and -heteroaryl benzoxazole derivatives.
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DOI: 10.4155/fmc-2022-0076
Abstract: Background: Phortress produces reactive electrophilic metabolites that form DNA adducts only in sensitive tumor cells. The authors converted the 2-phenylbenzothiazole nucleus in phortress to 2-aryl and -heteroaryl benzoxazole derivatives (11 new and 14 resynthesized). All… read more here.
Keywords: benzoxazole derivatives; activity; aryl heteroaryl; heteroaryl benzoxazole ... See more keywords