Organic photoredox catalytic amino-heteroarylation of unactivated olefins to access distal amino ketones.
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DOI: 10.1039/d1cc07189k
Abstract: Here we describe a metal-free amino-heteroarylation of unactivated olefins via organic photoredox catalysis, providing a concise and efficient approach for the rapid synthesis of various δ (β, ε)-amino ketones under mild conditions. This protocol demonstrates… read more here.
Keywords: amino heteroarylation; organic photoredox; heteroarylation unactivated; photoredox catalytic ... See more keywords
Heteroarylation of unactivated C–H bonds suitable for late-stage functionalization
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc04605a
Abstract: The late-stage introduction of diverse heterocycles onto complex small molecules enables efficient access to new medicinally relevant compounds. An attractive approach to such a transformation would utilize the ubiquitous aliphatic C–H bonds of a complex… read more here.
Keywords: late stage; stage functionalization; stage; heteroarylation unactivated ... See more keywords