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Published in 2018 at "Nature Catalysis"
DOI: 10.1038/s41929-018-0194-2
Abstract: The biosynthesis of the pharmacophoric tetrahydropyran of the clinically important antibiotic mupirocin remained enigmatic for a long time. Now, research shows that this ring is formed by a unique epoxidation–epoxide-opening cascade starting from a non-activated…
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Keywords:
via functionalization;
biosynthesis via;
biosynthesis;
heterocycle biosynthesis ... See more keywords