Synthesis and Pharmacological Activities of Chalcone and Its Derivatives Bearing N-Heterocyclic Scaffolds: A Review
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c01035
Abstract: The incorporation of heterocyclic moieties into the standard chemical structure with a biologically active scaffold has become of crucial practice for the construction of pharmacologically potent candidates in the drug arena. Currently, numerous kinds of… read more here.
Keywords: chalcone derivatives; bearing heterocyclic; pharmacological activities; heterocyclic scaffolds ... See more keywords
Transition metal-catalyzed sp3 C-H activation and intramolecular C-N coupling to construct nitrogen heterocyclic scaffolds.
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DOI: 10.1039/c9cc06609h
Abstract: Nitrogen heterocycles are of great medicinal importance, and the construction of nitrogen heterocyclic scaffolds has been one of the focuses in synthetic organic chemistry. Recently, the strategy of transition metal-catalyzed sp3 C-H activation and intramolecular… read more here.
Keywords: nitrogen; transition metal; heterocyclic scaffolds; nitrogen heterocyclic ... See more keywords
Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase
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DOI: 10.1039/d2ra03081k
Abstract: Heterocycles are the key structures in organic chemistry owing to their immense applications in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform various noteworthy functions in nature, medication, innovation etc. Most frequently, pure nitrogen… read more here.
Keywords: nitrogen oxygen; heterocyclic scaffolds; butyrylcholinesterase; oxygen sulfur ... See more keywords