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   Articles with "heterocyclic systems" as a keyword



Double Mannich reaction with ketones as a route to heterocyclic systems: A mini review

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recommendations! Published in 2024 at "Journal of Heterocyclic Chemistry"

DOI: 10.1002/jhet.4809

Abstract: Double Mannich reaction with ketones is of continuing interest, particularly, in the synthesis of aza‐ and diaza‐heterocycles, alkaloids, and medicinally relevant compounds. The present review deals with the most important literature on the utility of… read more here.

Keywords: review; double mannich; reaction ketones; heterocyclic systems ... See more keywords

A Universal Method for the Synthesis of new Heterocyclic Systems: Pyrimido[2,1‐f][1,2,4]triazines

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recommendations! Published in 2025 at "ChemistryOpen"

DOI: 10.1002/open.202400379

Abstract: Abstract The synthesis of pyrimido[2,1‐f][1,2,4]triazines was performed in four steps. Compounds obtained by acylation of the starting amino esters of thieno[2,3‐b]pyridines were reacted with various amines. The resulting amino derivatives underwent cyclization in the presence… read more here.

Keywords: universal method; new heterocyclic; pyrimido triazines; heterocyclic systems ... See more keywords
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Construction of N-Heterocyclic Systems Containing a Fully Substituted Allylic Carbon by Palladium/Phosphine Catalysis.

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recommendations! Published in 2018 at "Organic letters"

DOI: 10.1021/acs.orglett.8b03127

Abstract: The unique cyclization of benzamide derivatives that contain an alkyne by a Pd(0)/dialkyl(biaryl)phosphine catalytic system is reported. The reaction efficiently provides a variety of six-membered N-heterocyclic compounds that contain a fully substituted carbon center without… read more here.

Keywords: fully substituted; carbon; phosphine; systems containing ... See more keywords

Synthesis and Neurotropic Activity of New Heterocyclic Systems: Pyridofuro[3,2-d]pyrrolo[1,2-a]pyrimidines, Pyridofuro[3,2-d]pyrido[1,2-a]pyrimidines and Pyridofuro[3′,2′:4,5]pyrimido[1,2-a]azepines

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recommendations! Published in 2021 at "Molecules"

DOI: 10.3390/molecules26113320

Abstract: Background: Neurotic disturbances, anxiety, neurosis-like disorders, and stress situations are widespread. Benzodiazepine tranquillizers have been found to be among the most effective antianxiety drugs. The pharmacological action of benzodiazepines is due to their interaction with… read more here.

Keywords: pyrimidines pyridofuro; anticonvulsant activity; effect; activity ... See more keywords

2-(Methoxycarbonyl)thiophen-3-yl-diazonium Salts: Efficient Precursors for the Formation of C–C Bonds in Thiophene-Containing Heterocyclic Systems

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recommendations! Published in 2025 at "Molecules"

DOI: 10.3390/molecules30183758

Abstract: A first application of 2-(methoxycarbonyl)thiophen-3-diazonium salts in the halothienylation of α,β-unsaturated functionalized compounds under Meerwein reaction conditions is presented. This process provides thiophene-containing building blocks that can then undergo cyclization reactions with bisnucleophiles to synthesize… read more here.

Keywords: methoxycarbonyl thiophen; thiophen diazonium; diazonium salts; heterocyclic systems ... See more keywords