Articles with "heterodimer escherichia" as a keyword



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Structure of a reaction intermediate mimic in t6A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli

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Published in 2021 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab026

Abstract: Abstract The tRNA modification N6-threonylcarbamoyladenosine (t6A) is universally conserved in all organisms. In bacteria, the biosynthesis of t6A requires four proteins (TsaBCDE) that catalyze the formation of t6A via the unstable intermediate l-threonylcarbamoyl-adenylate (TC-AMP). While… read more here.

Keywords: heterodimer escherichia; t6a; active site; structure ... See more keywords