Hidden heritability due to heterogeneity across seven populations
Sign Up to like & getrecommendations! Published in 2017 at "Nature human behaviour"
DOI: 10.1038/s41562-017-0195-1
Abstract: Meta-analyses of genome-wide association studies, which dominate genetic discovery, are based on data from diverse historical time periods and populations. Genetic scores derived from genome-wide association studies explain only a fraction of the heritability estimates… read more here.
Keywords: genetic discovery; heterogeneity across; heritability; seven populations ... See more keywords
Termite mounds vary in their importance as sources of vegetation heterogeneity across savanna landscapes
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DOI: 10.1111/jvs.12560
Abstract: Questions Termite mounds are well known to host a suite of unique plants compared with the surrounding savanna matrix. However, most studies testing the significance of mounds for ecosystem heterogeneity have been conducted at single… read more here.
Keywords: savanna; heterogeneity; heterogeneity across; mound size ... See more keywords
Spatiotemporal Heterogeneity across Metastases and Organ-Specific Response Informs Drug Efficacy and Patient Survival in Colorectal Cancer
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DOI: 10.1158/0008-5472.can-20-3665
Abstract: These findings support the modification of RECIST criteria to include individual lesion response to improve assessments of drug efficacy. The sum of target lesions is routinely used to evaluate patient objective responses to treatment in… read more here.
Keywords: heterogeneity across; drug efficacy; response; heterogeneity ... See more keywords