Increased heterogeneity of brain perfusion is an early marker of central nervous system involvement in antiphospholipid antibody carriers
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0182344
Abstract: Objective The non-criteria neuropsychiatric manifestations of antiphospholipid syndrome include headache, dizziness, vertigo, seizure, depression and psychosis. There were still no objective methods qualified to detect the early central nervous system involvement in non-criteria antiphospholipid syndrome.… read more here.
Keywords: heterogeneity brain; antiphospholipid antibody; brain; brain perfusion ... See more keywords
Insights into the transcriptomic heterogeneity of brain endothelial cells in normal aging and Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2024 at "Neural Regeneration Research"
DOI: 10.4103/nrr.nrr-d-24-00695
Abstract: Drug development for Alzheimer’s disease is extremely challenging, as demonstrated by the repeated failures of amyloid-β-targeted therapeutics and the controversies surrounding the amyloid-β cascade hypothesis. More recently, advances in the development of Lecanemab, an anti-amyloid-β… read more here.
Keywords: alzheimer disease; disease; brain endothelial; heterogeneity brain ... See more keywords