NanoRNP Overcomes Tumor Heterogeneity in Cancer Treatment.
Sign Up to like & getrecommendations! Published in 2019 at "Nano letters"
DOI: 10.1021/acs.nanolett.9b02501
Abstract: Tumor heterogeneity has been one of the most important factors leading to the failure of conventional cancer therapies due to the accumulation of genetically distinct tumor-cell subpopulations during tumor development process. Due to the diversity… read more here.
Keywords: heterogeneity cancer; tumor heterogeneity; nanornp overcomes; tumor ... See more keywords
The heterogeneity of cancer‐associated fibroblast subpopulations: Their origins, biomarkers, and roles in the tumor microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15609
Abstract: The prognosis for patients with cancers known for a highly activated stromal reaction, including diffuse‐type (scirrhous) gastric cancer, consensus molecular subtype 4 (CMS4) colorectal cancer, and pancreatic ductal adenocarcinoma, is extremely poor. To explore the… read more here.
Keywords: cell; heterogeneity cancer; tumor microenvironment; cancer associated ... See more keywords
Epigenetic heterogeneity in cancer
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DOI: 10.1186/s40364-019-0174-y
Abstract: Phenotypic and functional heterogeneity is one of the hallmarks of human cancers. Tumor genotype variations among tumors within different patients are known as interpatient heterogeneity, and variability among multiple tumors of the same type arising… read more here.
Keywords: heterogeneity cancer; heterogeneity; epigenetic heterogeneity; cancer ... See more keywords
Spatial Transcriptomics for Tumor Heterogeneity Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.906158
Abstract: The molecular heterogeneity of cancer is one of the major causes of drug resistance that leads to treatment failure. Thus, better understanding the heterogeneity of cancer will contribute to more precise diagnosis and improved patient… read more here.
Keywords: tumor heterogeneity; heterogeneity; heterogeneity cancer; spatial transcriptomics ... See more keywords