Cellular Heterogeneity and Cooperativity in Glioma Persister Cells Under Temozolomide Treatment
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DOI: 10.3389/fcell.2022.835273
Abstract: We have observed a drug-tolerant/persister state in a human glioblastoma (GBM) cell line after exposure to temozolomide, the standard-of-care chemotherapeutic agent for GBM. We used a multicolor lentiviral genetic barcode labeling to follow cell population… read more here.
Keywords: four genes; temozolomide treatment; heterogeneity cooperativity; persister ... See more keywords