Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15700
Abstract: G-protein-coupled receptor (GPCR) expression is extensively studied in bulk cDNA, but heterogeneity and functional patterning of GPCR expression in individual vascular cells is poorly understood. Here, we perform a microfluidic-based single-cell GPCR expression analysis in… read more here.
Keywords: single cell; gpcr; heterogeneity functional; gpcr expression ... See more keywords
Single-Cell Transcriptome Profiling Reveals Neutrophil Heterogeneity and Functional Multiplicity in the Early Stage of Severe Burn Patients
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.792122
Abstract: The pathophysiological mechanisms, especially the roles of immune cells, underlying early stages of severe burn injury have not yet been fully clarified. Here, we analyzed circulating neutrophils (PMNs) in healthy donors and early burned patients… read more here.
Keywords: heterogeneity functional; heterogeneity; functional multiplicity; severe burn ... See more keywords
Plant Kinesin-12: Localization Heterogeneity and Functional Implications
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20174213
Abstract: Kinesin-12 family members are characterized by an N-terminal motor domain and the extensive presence of coiled-coil domains. Animal orthologs display microtubule plus-end directed motility, bundling of parallel and antiparallel microtubules, plus-end stabilization, and they play… read more here.
Keywords: kinesin localization; localization heterogeneity; plant kinesin; kinesin ... See more keywords