Fibroblast heterogeneity in prostate carcinogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer letters"
DOI: 10.1016/j.canlet.2021.10.028
Abstract: Our understanding of stromal components, specifically cancer-associated fibroblasts (CAF), in prostate cancer (PCa), has evolved from considering these cells as inert bystanders to acknowledging their significance as players in prostate tumorigenesis. CAF are multifaceted-they promote… read more here.
Keywords: caf; heterogeneity; heterogeneity prostate; fibroblast heterogeneity ... See more keywords
Harnessing the Heterogeneity of Prostate Cancer for Target Discovery Using Patient-Derived Explants
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14071708
Abstract: Simple Summary There is a widespread push toward more biologically relevant pre-clinical models of prostate cancer that can improve the discovery and translation of new drugs and biomarkers for this disease. Patient-derived explant culture is… read more here.
Keywords: cancer; prostate cancer; heterogeneity prostate; patient derived ... See more keywords