Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05614-4
Abstract: Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact methods for clearing, labeling, and… read more here.
Keywords: heterogeneous tissues; analysis; tissue; pathways clinical ... See more keywords
Quantitative analysis of drug distribution in heterogeneous tissues using dualâstacking capillary electrophoresisâmass spectrometry
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15988
Abstract: Intratumour heterogeneity frequently leads to drug resistance, which is a major issue in drug discovery. Drug distribution is one of the key factors for elucidating the resistance mechanism; however, quantitative and regional drug measurement is… read more here.
Keywords: heterogeneous tissues; analysis drug; quantitative analysis; drug distribution ... See more keywords