Heterologous biosynthesis of (+)-nootkatone in unconventional yeast Yarrowia lipolytica
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2018.05.023
Abstract: Abstract Yarrowia lipolytica is an unconventional yeast that is regarded as safe. It is the potential platform for terpenoids production because it possesses the endogenous MVA pathway which can provide precursors for terpenoids synthesis. Herein,… read more here.
Keywords: biosynthesis nootkatone; production; nootkatone; heterologous biosynthesis ... See more keywords
Glycerol improves heterologous biosynthesis of betulinic acid in engineered Yarrowia lipolytica
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Engineering Science"
DOI: 10.1016/j.ces.2018.10.052
Abstract: Abstract Glycerol is the main byproduct of the biodiesel production process and can be converted into valuable products by Yarrowia lipolytica. Betulinic acid is a pentacyclic triterpene with a variety of pharmacological properties. Herein we… read more here.
Keywords: glycerol; betulinic acid; heterologous biosynthesis; yarrowia lipolytica ... See more keywords
Total Heterologous Biosynthesis of Fungal Natural Products in Aspergillus nidulans.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c00487
Abstract: Fungal natural products comprise a wide range of bioactive compounds including important drugs and agrochemicals. Intriguingly, bioinformatic analyses of fungal genomes have revealed that fungi have the potential to produce significantly more natural products than… read more here.
Keywords: total heterologous; biosynthesis; natural products; heterologous biosynthesis ... See more keywords
Heterologous Biosynthesis of Type II Polyketide Products Using E. coli.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical biology"
DOI: 10.1021/acschembio.9b00827
Abstract: The heterologous biosynthesis of complex natural products has enabled access to polyketide, nonribosomal peptide, isoprenoid, and other compounds with wide-spanning societal value. Though several surrogate host systems exist, Escherichia coli is often a preferred choice… read more here.
Keywords: polyketide; type polyketide; biology; heterologous biosynthesis ... See more keywords
Heterologous Biosynthesis of Taraxerol by Engineered Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2022 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnac070
Abstract: Taraxerol is an oleanane-type pentacyclic triterpenoid compound distributed in many plant species that has good effects on the treatment of inflammation and tumors. However, the taraxerol content in medicinal plants is low, and chemical extraction… read more here.
Keywords: taraxerol; biosynthesis taraxerol; heterologous biosynthesis; saccharomyces cerevisiae ... See more keywords
Heterologous biosynthesis of isobavachalcone in tobacco based on in planta screening of prenyltransferases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1034625
Abstract: Isobavachalcone (IBC) is a prenylated chalcone mainly distributed in some Fabaceae and Moraceae species. IBC exhibits a wide range of pharmacological properties, including anti-bacterial, anti-viral, anti-inflammatory, and anti-cancer activities. In this study, we attempted to… read more here.
Keywords: biosynthesis; sffpt; isobavachalcone; tobacco ... See more keywords
Heterologous Biosynthesis of Health-Promoting Baicalein in Lycopersicon esculentum
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27103086
Abstract: Baicalein is a valuable flavonoid isolated from the medicinal plant Scutellaria baicalensis Georgi, which exhibits intensive biological activities, such as anticancer and antiviral activities. However, its production is limited in the root with low yield.… read more here.
Keywords: heterologous biosynthesis; baicalein; biosynthesis health; health promoting ... See more keywords
Heterologous Biosynthesis of Myxobacterial Antibiotic Miuraenamide A
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28062815
Abstract: The hard-to-culture slightly halophilic myxobacterium “Paraliomyxa miuraensis” SMH-27-4 produces antifungal cyclodepsipeptide miuraenamide A (1). Herein, the region (85.9 kbp) containing the biosynthetic gene cluster (BGC) coding the assembly of 1 was identified and heterologously expressed… read more here.
Keywords: biosynthesis myxobacterial; myxobacterial antibiotic; miuraenamide; heterologous biosynthesis ... See more keywords