CD4+ T Cells Are Dispensable for Induction of Broad Heterologous HIV Neutralizing Antibodies in Rhesus Macaques
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DOI: 10.3389/fimmu.2021.757811
Abstract: Induction of broadly neutralizing antibodies (bNAbs) is a major goal for HIV vaccine development. HIV envelope glycoprotein (Env)-specific bNAbs isolated from HIV-infected individuals exhibit substantial somatic hypermutation and correlate with T follicular helper (Tfh) responses.… read more here.
Keywords: hiv; neutralizing antibodies; heterologous hiv; rhesus macaques ... See more keywords