Characterization of the heterotrimeric G protein gene families in Triticum aestivum and related species
Sign Up to like & getrecommendations! Published in 2022 at "3 Biotech"
DOI: 10.1007/s13205-022-03156-9
Abstract: This study characterizes the heterotrimeric G protein gene families in Triticum aestivum, their tissue-specific expression patterns during development and in response to biotic and abiotic stress conditions. There are three Gα genes, three Gβ and… read more here.
Keywords: families triticum; heterotrimeric protein; protein gene; gene ... See more keywords
Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound β1-Adrenergic Receptor.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular cell"
DOI: 10.1016/j.molcel.2020.08.001
Abstract: Cardiac disease remains the leading cause of morbidity and mortality worldwide. The β1-adrenergic receptor (β1-AR) is a major regulator of cardiac functions and is downregulated in the majority of heart failure cases. A key physiological… read more here.
Keywords: adrenergic receptor; heterotrimeric protein; activation; activation heterotrimeric ... See more keywords
Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update
Sign Up to like & getrecommendations! Published in 2018 at "Laboratory Investigation"
DOI: 10.1038/labinvest.2017.103
Abstract: Heterotrimeric G proteins are pivotal mediators of cellular signal transduction in eukaryotic cells and abnormal G-protein signaling plays an important role in numerous diseases. During the last two decades it has become evident that the… read more here.
Keywords: protein; regulation heterotrimeric; protein signaling; heterotrimeric proteins ... See more keywords
Signal transduction by plant's heterotrimeric G-protein.
Sign Up to like & getrecommendations! Published in 2020 at "Plant biology"
DOI: 10.1111/plb.13172
Abstract: Heterotrimeric G-proteins are complexes that regulate important signalling pathways essential for growth and development in both plants and animals. Although plant cells are composed of the core components (Gα, Gβ and Gγ subunits) found in… read more here.
Keywords: signal transduction; transduction plant; plant heterotrimeric; plant ... See more keywords
Ligand-induced dynamics of heterotrimeric G protein-coupled receptor-like kinase complexes
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171854
Abstract: Background Arabidopsis, 7-transmembrane Regulator of G signaling protein 1 (AtRGS1) modulates canonical G protein signaling by promoting the inactive state of heterotrimeric G protein complex on the plasma membrane. It is known that plant leucine-rich… read more here.
Keywords: protein; reactive oxygen; atrgs1; receptor like ... See more keywords
Genetic relationships between the RACK1 homolog cpc-2 and heterotrimeric G protein subunit genes in Neurospora crassa
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0223334
Abstract: Receptor for Activated C Kinase-1 (RACK1) is a multifunctional eukaryotic scaffolding protein with a seven WD repeat structure. Among their many cellular roles, RACK1 homologs have been shown to serve as alternative Gβ subunits during… read more here.
Keywords: protein; neurospora crassa; cpc; heterotrimeric protein ... See more keywords
Effective strategies on heterologous expression of plant heterotrimeric G-protein γ subunits without Gβ subunit partners.
Sign Up to like & getrecommendations! Published in 2022 at "Protein and peptide letters"
DOI: 10.2174/0929866529666220203094448
Abstract: BACKGROUND In plants, heterotrimeric G-protein (Gγ) subunits are diverse, and they have structural plasticity to provide functional selectivity to the heterotrimer. Although the Gβ and Gγ subunits dimerize to function in the signaling pathway, the… read more here.
Keywords: subunit partners; protein subunits; expression; plant ... See more keywords
Heterotrimeric G Protein Α-Subunits - Structures, Peptide-Derived Inhibitors, and Mechanisms.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220308112424
Abstract: G protein-coupled receptors are the largest protein family in the human body and represent the most important class of drug targets. They receive extracellular signals and transduce them into the cytosol. The guanine nucleotide-binding G… read more here.
Keywords: subunits structures; peptide derived; structures peptide; protein subunits ... See more keywords
Heterotrimeric G-Protein Signalers and RGSs in Aspergillus fumigatus
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens"
DOI: 10.3390/pathogens9110902
Abstract: The heterotrimeric G-protein (G-protein) signaling pathway is one of the most important signaling pathways that transmit external signals into the inside of the cell, triggering appropriate biological responses. The external signals are sensed by various… read more here.
Keywords: protein; aspergillus fumigatus; protein signaling; protein signalers ... See more keywords
Heterotrimeric G Protein Signaling in Abiotic Stress
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11070876
Abstract: As sessile organisms, plants exhibit extraordinary plasticity and have evolved sophisticated mechanisms to adapt and mitigate the adverse effects of environmental fluctuations. Heterotrimeric G proteins (G proteins), composed of α, β, and γ subunits, are… read more here.
Keywords: stress; response; abiotic stress; signaling abiotic ... See more keywords