The βγ subunit of heterotrimeric G proteins interacts with actin filaments during neuronal differentiation.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.02.095
Abstract: The βγ subunit of heterotrimeric G proteins, a key molecule in the G protein-coupled receptors (GPCRs) signaling pathway, has been shown to be an important factor in the modulation of the microtubule cytoskeleton. Gβγ has… read more here.
Keywords: subunit heterotrimeric; heterotrimeric proteins; interacts actin; actin filaments ... See more keywords
Heterotrimeric G-proteins mediated hormonal responses in plants.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109799
Abstract: Phytohormones not only orchestrate intrinsic developmental programs from germination to senescence but also regulate environmental inputs through complex signalling pathways. Despite building an own signalling network, hormones mutually contribute several signalling systems, which are also… read more here.
Keywords: hormonal responses; proteins mediated; heterotrimeric proteins; responses plants ... See more keywords
Heterotrimeric G Proteins as Therapeutic Targets in Drug Discovery.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b01452
Abstract: Heterotrimeric G proteins are molecular switches in GPCR signaling pathways and regulate a plethora of physiological and pathological processes. GPCRs are efficient drug targets and more than 30% of the drugs in use target them.… read more here.
Keywords: targets drug; therapeutic targets; drug; heterotrimeric proteins ... See more keywords
Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update
Sign Up to like & getrecommendations! Published in 2018 at "Laboratory Investigation"
DOI: 10.1038/labinvest.2017.103
Abstract: Heterotrimeric G proteins are pivotal mediators of cellular signal transduction in eukaryotic cells and abnormal G-protein signaling plays an important role in numerous diseases. During the last two decades it has become evident that the… read more here.
Keywords: protein; regulation heterotrimeric; protein signaling; heterotrimeric proteins ... See more keywords
Heterotrimeric G proteins regulate planarian regeneration and behavior
Sign Up to like & getrecommendations! Published in 2022 at "Genetics"
DOI: 10.1093/genetics/iyad019
Abstract: G protein-coupled receptors (GPCRs) play broad roles in development and stem cell biology, but few roles for GPCR signaling in complex tissue regeneration have been uncovered. Planarian flatworms robustly regenerate all tissues and provide a… read more here.
Keywords: regeneration; behavior; gpcr signaling; heterotrimeric proteins ... See more keywords
Plant receptor-like kinase signaling through heterotrimeric G-proteins
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/eraa016
Abstract: Abstract Heterotrimeric G-proteins regulate multiple aspects of plant growth, development, and response to biotic and abiotic stresses. While the core components of heterotrimeric G-proteins and their basic biochemistry are similar in plants and metazoans, key… read more here.
Keywords: plant; plant receptor; heterotrimeric proteins; receptor like ... See more keywords
Heterotrimeric G Proteins in Plants: Canonical and Atypical Gα Subunits
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222111841
Abstract: Heterotrimeric GTP-binding proteins (G proteins), consisting of Gα, Gβ and Gγ subunits, transduce signals from a diverse range of extracellular stimuli, resulting in the regulation of numerous cellular and physiological functions in Eukaryotes. According to… read more here.
Keywords: plant; plants canonical; heterotrimeric proteins; atypical subunits ... See more keywords