Comparison of the characteristics at diagnosis and treatment of children with heterozygous familial hypercholesterolaemia (FH) from eight European countries
Sign Up to like & getrecommendations! Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2019.11.012
Abstract: Background and aims For children with heterozygous familial hypercholesterolaemia (HeFH), European guidelines recommend consideration of statin therapy by age 8–10 years for those with a low density lipoprotein cholesterol (LDL-C) >3.5 mmol/l, and dietary and… read more here.
Keywords: ldl mmol; diagnosis; treatment; familial hypercholesterolaemia ... See more keywords
Prevalence of heterozygous familial hypercholesterolemia and combined hyperlipidemia phenotype in very young survivors of myocardial infarction and their association with the severity of atheromatous burden.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2019.02.007
Abstract: BACKGROUND Heterozygous familial hypercholesterolemia (HeFH) and combined hyperlipidemia (CHL) phenotype are associated with premature myocardial infarction (MI). OBJECTIVE To assess the prevalence of HeFH and CHL phenotype among young survivors of MI and compare patients'… read more here.
Keywords: heterozygous familial; familial hypercholesterolemia; phenotype; chl phenotype ... See more keywords
Prevalence, risk factor burden, and severity of coronary artery disease in patients with heterozygous familial hypercholesterolemia hospitalized for an acute myocardial infarction: Data from the French RICO survey.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2019.06.005
Abstract: BACKGROUND Individuals with heterozygous familial hypercholesterolemia (FH) are at high risk of early myocardial infarction (MI). However, coronary artery disease (CAD) burden of FH remains not well described, especially for French patients. OBJECTIVE The objective… read more here.
Keywords: heterozygous familial; familial hypercholesterolemia; prevalence; burden ... See more keywords
Treatment of heterozygous familial hypercholesterolemia: what does the future hold?
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2020.1839417
Abstract: ABSTRACT Introduction Heterozygous familial hypercholesterolemia (heFH) is a common metabolic disease associated with increased cardiovascular risk. Despite treatment with the currently available lipid-lowering agents (statins, ezetimibe, and proprotein convertase subtilisin/kexin type 9 inhibitors), a substantial… read more here.
Keywords: treatment; patients hefh; heterozygous familial; lipid lowering ... See more keywords
High‐density lipoprotein‐associated sphingosine‐1‐phosphate activity in heterozygous familial hypercholesterolaemia
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DOI: 10.1111/eci.12699
Abstract: Patients with heterozygous familial hypercholesterolaemia (FH) suffer from high plasma cholesterol and an environment of increased oxidative stress. We examined its potential effects on high‐density lipoprotein (HDL)‐associated sphingosine‐1‐phosphate (S1P) content (HDL‐S1P) and HDL‐mediated protection against… read more here.
Keywords: high density; density lipoprotein; familial hypercholesterolaemia; associated sphingosine ... See more keywords
Response by Kusters et al to Letter Regarding Article, "Effect of Rosuvastatin on Carotid Intima-Media Thickness in Children With Heterozygous Familial Hypercholesterolemia: The CHARON Study (Hypercholesterolemia in Children and Adolescents Taking Rosuvastatin Open Label)".
Sign Up to like & getrecommendations! Published in 2018 at "Circulation"
DOI: 10.1161/circulationaha.117.031676
Abstract: We appreciate the comments of Dr Koh regarding our recent publication in Circulation .1 We comment here on the issues raised. Undoubtedly, patients with heterozygous familial hypercholesterolemia (HeFH) should be treated with lipid-lowering medication from… read more here.
Keywords: hypercholesterolemia; rosuvastatin; hypercholesterolemia children; heterozygous familial ... See more keywords
Heterozygous Familial Hypercholesterolemia With APOE Haplotype: A Prospective Harbinger of a Catastrophic Cardiovascular Event
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DOI: 10.14740/cr548w
Abstract: We report a very young man with heterozygous familial hypercholesterolemia (FH) with APOE haplotype and a significant cardiac family history who underwent cardiac catheterization for intermittent episodes of exertional dyspnea and was noted to have… read more here.
Keywords: familial hypercholesterolemia; heterozygous familial; hypercholesterolemia apoe; apoe haplotype ... See more keywords
Heterozygous Familial Hyperlipidemia in a Fighter Pilot.
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DOI: 10.3357/amhp.5906.2021
Abstract: BACKGROUND: Heterozygous familial hypercholesterolemia (HeFH) is an autosomal dominant disease characterized by elevated low-density lipoprotein cholesterol (LDL-C) that increases risk for clinically significant atherosclerotic cardiovascular disease (ASCVD). This common (1:220) disease is present within the… read more here.
Keywords: heterozygous familial; familial hyperlipidemia; pilot; disease ... See more keywords