Articles with "heterozygous notch1" as a keyword



Photo from wikipedia

Heterozygous NOTCH1 Variants Cause CNS Immune Activation and Microangiopathy

Sign Up to like & get
recommendations!
Published in 2022 at "Annals of Neurology"

DOI: 10.1002/ana.26477

Abstract: NOTCH1 belongs to the NOTCH family of proteins that regulate cell fate and inflammatory responses. Somatic and germline NOTCH1 variants have been implicated in cancer, Adamsā€Oliver syndrome, and cardiovascular defects. We describe 7 unrelated patients… read more here.

Keywords: variants cause; cns immune; notch1 variants; heterozygous notch1 ... See more keywords