Porphobilinogen synthase: An equilibrium of different assemblies in human health.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2019.11.003
Abstract: Porphobilinogen synthase (PBGS) is an essential enzyme that catalyzes an early step in heme biosynthesis. An unexpected human PBGS quaternary structure dynamic drove the definition of morpheeins, which are protein multimers that dissociate, change shape,… read more here.
Keywords: porphobilinogen synthase; hexamer; equilibrium; pbgs ... See more keywords
The Phe-Ile Zipper: A Specific Interaction Motif Drives Antiparallel Coiled-Coil Hexamer Formation.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b00756
Abstract: Coiled coils are a robust motif for exploring amino acid interactions, generating unique supramolecular structures, and expanding the functional properties of biological materials. A recently discovered antiparallel coiled-coil hexamer (ACC-Hex, peptide 1) exhibits a unique… read more here.
Keywords: phe ile; acc hex; ile zipper; phe ... See more keywords
Spin triplet ground-state in the copper hexamer compounds A2Cu3O(SO4)3(A=Na,K)
Sign Up to like & getrecommendations! Published in 2018 at "Physical Review B"
DOI: 10.1103/physrevb.98.180410
Abstract: The compounds A2Cu3O(SO4)3 (A=Na,K) are characterized by copper hexamers which are weakly coupled along the b-axis to realize one-dimensional antiferromagnetic chains below TN=3 K, whereas the interchain interactions along the a- and c-axes are negligible.… read more here.
Keywords: copper; triplet ground; a2cu3o so4; compounds a2cu3o ... See more keywords
A Broad-Spectrum Antiviral Molecule, Protoporphyrin IX, Acts as a Moderator of HIV-1 Capsid Assembly by Targeting the Capsid Hexamer
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02663-22
Abstract: CA and its assembled viral core play essential roles in distinct steps during HIV-1 replication, including reverse transcription, integration, nuclear entry, virus assembly, and maturation through CA–CA or CA–host factor interactions. These functions of CA… read more here.
Keywords: hiv; ppix; molecule protoporphyrin; hexamer ... See more keywords
MCMBP promotes the assembly of the MCM2–7 hetero-hexamer to ensure robust DNA replication in human cells
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.77393
Abstract: The MCM2–7 hetero-hexamer is the replicative DNA helicase that plays a central role in eukaryotic DNA replication. In proliferating cells, the expression level of the MCM2–7 hexamer is kept high, which safeguards the integrity of… read more here.
Keywords: hetero hexamer; dna; hexamer; mcm2 hetero ... See more keywords