Methyl jasmonate treatment increases podophyllotoxin production in Podophyllum hexandrum roots under glasshouse conditions
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DOI: 10.1007/s11104-017-3245-6
Abstract: Background and aimThe endangered Podophyllum hexandrum is an important industrial source of podophyllotoxin, which is a precursor for the anticancer drugs etoposide and teniposide. Attempts to obtain podophyllotoxin through cell cultures or chemical synthesis have… read more here.
Keywords: methyl jasmonate; production; formation; hexandrum ... See more keywords
Mapping podophyllotoxin biosynthesis and growth-related transcripts with high elevation in Sinopodophyllum hexandrum
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DOI: 10.1016/j.indcrop.2018.08.007
Abstract: Abstract Sinopodophyllum hexandrum, a perennial rhizomatous herb that produces the anti-cancer metabolite podophyllotoxin (PPT), is distributed in the Himalayan region. While greater plant growth and PPT accumulation is observed at higher compared with lower elevations,… read more here.
Keywords: biosynthesis; sinopodophyllum hexandrum; hexandrum; elevation ... See more keywords
Light-Induced Flavonoid Biosynthesis in Sinopodophyllum hexandrum with High-Altitude Adaptation
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DOI: 10.3390/plants12030575
Abstract: Sinopodophyllum hexandrum is a perennial alpine herb producing the anti-cancer metabolite podophyllotoxin (PPT). Although the adaptation of S. hexandrum to high altitudes has been demonstrated and the effects of temperature, precipitation, and UV-B light on… read more here.
Keywords: flavonoid biosynthesis; sinopodophyllum hexandrum; hexandrum high; altitude ... See more keywords