Articles with "hexapeptide core" as a keyword



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Protection against β‐amyloid neurotoxicity by a non‐toxic endogenous N‐terminal β‐amyloid fragment and its active hexapeptide core sequence

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Published in 2018 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.14257

Abstract: High levels (μM) of beta amyloid (Aβ) oligomers are known to trigger neurotoxic effects, leading to synaptic impairment, behavioral deficits, and apoptotic cell death. The hydrophobic C‐terminal domain of Aβ, together with sequences critical for… read more here.

Keywords: hexapeptide core; core sequence; terminal fragment; fragment active ... See more keywords