Genomics-Driven Discovery of Chlorinated Cyclic Hexapeptides Ulleungmycins A and B from a Streptomyces Species.
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DOI: 10.1021/acs.jnatprod.7b00660
Abstract: Analysis of the genome sequence of Streptomyces sp. KCB13F003 showed the presence of a cryptic gene cluster encoding flavin-dependent halogenase and nonribosomal peptide synthetase. Pleiotropic approaches using multiple culture media followed by LC-MS-guided isolation and… read more here.
Keywords: cyclic hexapeptides; driven discovery; hexapeptides ulleungmycins; discovery chlorinated ... See more keywords