New natural inhibitors of hexokinase 2 (HK2): Steroids from Ganoderma sinense.
Sign Up to like & getrecommendations! Published in 2018 at "Fitoterapia"
DOI: 10.1016/j.fitote.2018.01.001
Abstract: Hexokinase 2 (HK2), a rate-limiting enzyme in the first step of glycolysis pathway, expresses at high level in cancer cells compared with normal cells. HK2 provides a new target for cancer therapy due to its… read more here.
Keywords: natural inhibitors; ganoderma sinense; inhibitors hexokinase; new natural ... See more keywords
Advances in the Study of Hexokinase 2 (HK2) Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520623666221020092423
Abstract: Purpose The Warburg effect is an important metabolic feature of tumours, and hexokinase is the first rate-limiting enzyme of the glycolytic pathway during tumour metabolism. Among hexokinase subtypes, hexokinase 2 (HK2) is increasingly proving to… read more here.
Keywords: study hexokinase; advances study; hexokinase hk2; chemistry ... See more keywords