The role of hexon in egg drop syndrome virus (EDSV) inducing apoptosis in duck embryo fibroblast cells.
Sign Up to like & getrecommendations! Published in 2017 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2017.07.015
Abstract: Although extensive efforts have been made to understand adenovirus infection in human cells, little is known for egg drop syndrome virus (EDSV) infection in the avian-derived cells. In this study, the effects of EDSV infection… read more here.
Keywords: egg drop; infection; edsv; hexon ... See more keywords
Hexon and fiber of adenovirus type 14 and 55 are major targets of neutralizing antibody but only fiber-specific antibody contributes to cross-neutralizing activity.
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2018.03.002
Abstract: Re-emerging human adenoviruses type 14 (HAdV14) and 55 (HAdV55) represent two highly virulent adenoviruses. The neutralizing antibody (nAb) responses elicited by infection or immunization remain largely unknown. Herein, we generated hexon-chimeric HAdV14 viruses harboring each… read more here.
Keywords: hadv14 hadv55; neutralizing antibody; antibody; fiber ... See more keywords
Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00807-22
Abstract: FAdV-4, as the main cause of HHS, has quickly spread all over the world in recent years, seriously threatening the poultry industry. The aim of this study was to identify the important host proteins that… read more here.
Keywords: dnajc7; hexon; replication; viral hexon ... See more keywords
Molecular Mechanism of Adenovirus Late Protein L4-100K Chaperones the Trimerization of Hexon
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01467-22
Abstract: Adenovirus vectors have been widely used in clinical trials of vaccines and gene therapy, although some deficiencies remain. Chimeric modification of the hexon was expected to improve the potency of preexisting immune evasion and targeting,… read more here.
Keywords: hexon; trimerization; chaperone; protein 100k ... See more keywords
Identification of a Critical and Conformational Neutralizing Epitope in Human Adenovirus Type 4 Hexon
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.01643-17
Abstract: ABSTRACT Human adenovirus type 4 (HAdV-4) is an epidemic virus that contributes to serious acute respiratory disease (ARD) in both pediatric and adult patients. However, no licensed drug or vaccine is currently available to the… read more here.
Keywords: adenovirus type; neutralizing epitope; hadv; human adenovirus ... See more keywords
Binding of adenovirus species C hexon to prothrombin and the influence of hexon on vector properties in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010859
Abstract: The majority of adenovirus (Ad) vectors are based on human Ad type 5, which is a member of Ad species C. Species C also includes the closely-related types 1, 2, 6, 57 and 89. It… read more here.
Keywords: coagulation; hexon; ad5 vectors; liver tropism ... See more keywords
Oral Immunization of Recombinant Lactococcus lactis and Enterococcus faecalis Expressing Dendritic Cell Targeting Peptide and Hexon Protein of Fowl Adenovirus 4 Induces Protective Immunity Against Homologous Infection
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.632218
Abstract: Hepatitis-hydropericardium syndrome (HPS) causes severe economic losses in the global poultry industry. The present study aims to explore oral immunization of recombinant Lactococcus lactis and Enterococcus faecalis expressing Hexon protein of fowl adenovirus 4 (FAdV-4).… read more here.
Keywords: protein; hexon cwa; faecalis; hexon protein ... See more keywords