The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to maintain cardiac homeostasis
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DOI: 10.1038/s41467-024-55557-4
Abstract: Energy deprivation and metabolic rewiring of cardiomyocytes are widely recognized hallmarks of heart failure. Here, we report that HEY2 (a Hairy/Enhancer-of-split-related transcriptional repressor) is upregulated in hearts of patients with dilated cardiomyopathy. Induced Hey2 expression… read more here.
Keywords: transcriptional repressor; hey2; repressor hey2; hey2 regulates ... See more keywords