Neuromodulatory effects of green coffee bean extract against brain damage in male albino rats with experimentally induced diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-020-00583-6
Abstract: Diabetes mellitus is an increasing metabolic disease worldwide associated with central nervous system disorders. Coffee is a widely consumed beverage that enriched with antioxidants with numerous medicinal applications. Accordingly, the present study aimed to investigate… read more here.
Keywords: hfd; green coffee; coffee bean; hfd stz ... See more keywords
Alleviative effects of 20(R)-Rg3 on HFD/STZ-induced diabetic nephropathy via MAPK/NF-κB signaling pathways in C57BL/6 mice.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113500
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Diabetic nephropathy (DN) is a major complication of diabetes. The kidney disease develops in nearly 20%∼40 % of type 2 diabetes (T2D) patients. Ginseng is the root of Panax ginseng C. A. Meyer… read more here.
Keywords: hfd stz; stz; diabetic nephropathy; alleviative effects ... See more keywords
Chitosan-Stabilized Selenium Nanoparticles and Metformin Synergistically Rescue Testicular Oxidative Damage and Steroidogenesis-Related Genes Dysregulation in High-Fat Diet/Streptozotocin-Induced Diabetic Rats
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DOI: 10.3390/antiox10010017
Abstract: Background: this study examined the metformin (MF) and/or chitosan stabilized selenium nanoparticles (CH-SeNPs) efficacy to alleviate the male reproductive function impairment in a high-fat diet feed with low-dose streptozotocin (HFD/STZ) induced type 2 diabetes mellitus… read more here.
Keywords: steroidogenesis related; diabetic rats; related genes; hfd stz ... See more keywords
The Role of NF-κB and Bax/Bcl-2/Caspase-3 Signaling Pathways in the Protective Effects of Sacubitril/Valsartan (Entresto) against HFD/STZ-Induced Diabetic Kidney Disease
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10112863
Abstract: LCZ696 (valsartan/sacubitril) has the potential to slow the progression of diabetic kidney disease (DKD) according to previous reports. However, the renoprotective mechanism underlying LCZ696 remains unknown. This study aimed to investigate the therapeutic potential and… read more here.
Keywords: hfd stz; bax; kidney disease; diabetic kidney ... See more keywords
Ranolazine Attenuates Brain Inflammation in a Rat Model of Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416160
Abstract: Recent studies suggest a pathogenetic association between metabolic disturbances, including type 2 diabetes (T2DM), and cognitive decline and indicate that T2DM may represent a risk factor for Alzheimer’s disease (AD). There are a number of… read more here.
Keywords: rat model; hfd stz; hfd; type diabetes ... See more keywords