Hfe Actions in Kupffer Cells Are Dispensable for Hepatic and Systemic Iron Metabolism
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DOI: 10.3390/ijms24108948
Abstract: Mutations in the HFE/Hfe gene cause Hereditary Hemochromatosis (HH), a highly prevalent genetic disorder characterized by elevated iron deposition in multiple tissues. HFE acts in hepatocytes to control hepcidin expression, whereas HFE actions in myeloid… read more here.
Keywords: hfe actions; hepatic systemic; iron; kupffer cells ... See more keywords