Volatile Anesthetic Sevoflurane Precursor 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) Exerts an Anti-Prion Activity in Prion-Infected Culture Cells
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical Research"
DOI: 10.1007/s11064-021-03344-8
Abstract: Prion disease is a neurodegenerative disorder with progressive neurologic symptoms and accelerated cognitive decline. The causative protein of prion disease is the prion protein (PrP), and structural transition of PrP from the normal helix rich… read more here.
Keywords: hfip; prion; prion disease; anesthetic sevoflurane ... See more keywords
Comparison of the Level of Free Hexafluoro-Isopropanol in Adults' Blood and the Incidence of Emergence Agitation After Anesthesia With Different Concentrations of Sevoflurane in Laparoscopic Gastrointestinal Surgery: A Randomized Controlled Clinical Trial.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2019.08.022
Abstract: PURPOSE The aim of the study is to compare the free hexafluoro-isopropanol (HFIP) concentration in adults' blood and the incidence of emergence agitation (EA) after inhaled different concentrations of sevoflurane. METHODS Sixty adult patients planning… read more here.
Keywords: hfip; incidence; surgery; different concentrations ... See more keywords
Toward Highly Reversible Magnesium–Sulfur Batteries with Efficient and Practical Mg[B(hfip)4]2 Electrolyte
Sign Up to like & getrecommendations! Published in 2018 at "ACS energy letters"
DOI: 10.1021/acsenergylett.8b01061
Abstract: The rechargeable magnesium (Mg) battery has been considered a promising candidate for future battery generations due to unique advantages of the Mg metal anode. The combination of Mg with a sulfur cathode is one of… read more here.
Keywords: hfip; magnesium; electrolyte; magnesium sulfur ... See more keywords
Controlling the regioselectivity of the bromolactonization reaction in HFIP
Sign Up to like & getrecommendations! Published in 2024 at "Chemical Science"
DOI: 10.1039/d4sc01503g
Abstract: The halolactonization reaction provides rapid access to densely functionalized lactones from unsaturated carboxylic acids. The endo/exo regioselectivity of this cyclization reaction is primarily determined by the electronic stabilization of alkene substituents, thus making it inherently… read more here.
Keywords: reaction; regioselectivity bromolactonization; regioselectivity; controlling regioselectivity ... See more keywords
Quantifying hexafluoroisopropanol's hydrogen bond donor ability: infrared photodissociation spectroscopy of halide anion HFIP complexes
Sign Up to like & getrecommendations! Published in 2025 at "Chemical Science"
DOI: 10.1039/d4sc08456j
Abstract: We report on the gas phase vibrational spectroscopy (3500–950 cm−1) of halide anion complexes with 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) and its partially deuterated analogue (HFIP-d1). Infrared photodissociation spectra of messenger-tagged X−(HFIP/HFIP-d1), with X− = Cl−, Br−, and… read more here.
Keywords: hydrogen bond; spectroscopy; hfip; halide anion ... See more keywords
Use-dependent inhibition of glycine-activated chloride current in rat neurons by &bgr;-amyloid peptide pretreated with hexafluoroisopropanol
Sign Up to like & getrecommendations! Published in 2017 at "NeuroReport"
DOI: 10.1097/wnr.0000000000000801
Abstract: Hexafluoroisopropanol (HFIP) is a nonpolar organic solvent that is often used to prepare &bgr;-amyloid peptide (A&bgr;) samples. In this work, we compare the effects of two different species derived from synthetic A&bgr;1–42 and prepared without… read more here.
Keywords: hfip; bgr; amyloid peptide; bgr hfip ... See more keywords
Hierarchical Nanoheterostructure of HFIP-Grafted α-Fe2O3@Multiwall Carbon Nanotubes as High-Performance Chemiresistive Sensors for Nerve Agents
Sign Up to like & getrecommendations! Published in 2024 at "Nanomaterials"
DOI: 10.3390/nano14030305
Abstract: New and efficient sensors of nerve agents are urgently demanded to prevent them from causing mass casualties in war or terrorist attacks. So, in this work, a novel hierarchical nanoheterostructure was synthesized via the direct… read more here.
Keywords: sensors nerve; nerve agents; dmmp; performance ... See more keywords