Articles with "hfq" as a keyword



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Hfq chaperone brings speed dating to bacterial sRNA

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Published in 2018 at "Wiley Interdisciplinary Reviews: RNA"

DOI: 10.1002/wrna.1475

Abstract: Hfq is a ubiquitous, Sm‐like RNA binding protein found in most bacteria and some archaea. Hfq binds small regulatory RNAs (sRNAs), facilitates base pairing between sRNAs and their mRNA targets, and directly binds and regulates… read more here.

Keywords: hfq; chaperone brings; srna; rna ... See more keywords
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Hfq, a global regulator contributes to the virulence of Vibrio splendidus AJ01

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Published in 2022 at "Aquaculture"

DOI: 10.1016/j.aquaculture.2021.737416

Abstract: Abstract Hfq acts as an RNA-binding protein that ubiquitously exists in bacteria and contributes to global regulation of a wide range of gene expression. Vibrio splendidus is an important pathogen of sea cucumber A. japonicus,… read more here.

Keywords: system; hfq; splendidus; flagellar assembly ... See more keywords
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A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation

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Published in 2021 at "Molecular Cell"

DOI: 10.1016/j.molcel.2021.05.032

Abstract: Summary Polynucleotide phosphorylase (PNPase) is an ancient exoribonuclease conserved in the course of evolution and is found in species as diverse as bacteria and humans. Paradoxically, Escherichia coli PNPase can act not only as an… read more here.

Keywords: pnpase; cooperative pnpase; hfq; rna carrier ... See more keywords
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Superconductor digital circuits with π junctions alone

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Published in 2023 at "Applied Physics Letters"

DOI: 10.1063/5.0144604

Abstract: We adopt superconductor/ferromagnet/insulator/superconductor (SFIS) Josephson junctions (JJs) as both switching JJs and intrinsic π phase shifters in superconductor digital circuits. The critical current density (Jc) and characteristic voltage (Vc) of the SFIS junctions are about… read more here.

Keywords: junctions alone; superconductor digital; digital circuits; phase ... See more keywords
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Intrinsically disordered interaction network in an RNA chaperone revealed by native mass spectrometry

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2208780119

Abstract: RNA-binding proteins contain intrinsically disordered regions whose functions in RNA recognition are poorly understood. The RNA chaperone Hfq is a homohexamer that contains six flexible C-terminal domains (CTDs). The effect of the CTDs on Hfq’s… read more here.

Keywords: mass spectrometry; rna binding; network; hfq ... See more keywords
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Stabilization of Hfq-mediated translational repression by the co-repressor Crc in Pseudomonas aeruginosa

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Published in 2021 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab510

Abstract: Abstract In Pseudomonas aeruginosa the RNA chaperone Hfq and the catabolite repression control protein (Crc) govern translation of numerous transcripts during carbon catabolite repression. Here, Crc was shown to enhance Hfq-mediated translational repression of several… read more here.

Keywords: hfq; pseudomonas aeruginosa; translational repression; hfq mediated ... See more keywords
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Photorhabdus‐nematode symbiosis is dependent on hfq‐mediated regulation of secondary metabolites

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Published in 2017 at "Environmental Microbiology"

DOI: 10.1111/1462-2920.13502

Abstract: Photorhabdus luminescens maintains a symbiotic relationship with the nematodes Heterorhabditis bacteriophora and together they infect and kill insect larvae. To maintain this symbiotic relationship, the bacteria must produce an array of secondary metabolites to assist… read more here.

Keywords: hfq; nematode symbiosis; photorhabdus nematode; secondary metabolites ... See more keywords
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Influence of the Hfq and Crc global regulators on the control of iron homeostasis in Pseudomonas putida

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Published in 2018 at "Environmental Microbiology"

DOI: 10.1111/1462-2920.14263

Abstract: Metabolically versatile bacteria use catabolite repression control to select their preferred carbon sources, thus optimizing carbon metabolism. In pseudomonads, this occurs through the combined action of the proteins Hfq and Crc, which form stable tripartite… read more here.

Keywords: hfq crc; iron; iron homeostasis; hfq ... See more keywords
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RNA-binding protein Hfq downregulates locus of enterocyte effacement-encoded regulators independent of small regulatory RNA in enterohemorrhagic Escherichia coli.

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Published in 2021 at "Molecular microbiology"

DOI: 10.1111/mmi.14799

Abstract: Enterohemorrhagic Escherichia coli (EHEC) causes severe human diseases worldwide. The type three secretion system and effector proteins are essential for EHEC infection, and are encoded by the locus of enterocyte effacement (LEE). RNA-binding protein Hfq… read more here.

Keywords: hfq; escherichia coli; rna; rna binding ... See more keywords
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Multifaceted Interplay between Hfq and the Small RNA GssA in Pseudomonas aeruginosa

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Published in 2022 at "mBio"

DOI: 10.1128/mbio.02418-22

Abstract: The pathogenic lifestyle of the bacterium Pseudomonas aeruginosa, a leading cause of life-threatening infections in the airways of cystic fibrosis patients, is based on the fine regulation of virulence-associated factors. Regulatory small RNAs (sRNAs) and… read more here.

Keywords: pseudomonas aeruginosa; role; gssa; interplay hfq ... See more keywords
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Hfq Globally Binds and Destabilizes sRNAs and mRNAs in Yersinia pestis

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Published in 2019 at "mSystems"

DOI: 10.1128/msystems.00245-19

Abstract: Discovered in 1968 as an Escherichia coli host factor that was essential for replication of the bacteriophage Qβ, the Hfq protein is a ubiquitous and highly abundant RNA-binding protein in many bacteria. With the assistance… read more here.

Keywords: base pairing; yersinia pestis; hfq; srna mrna ... See more keywords