Baseline characteristics of 547 new onset heart failure patients in the PREFERS heart failure study.
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DOI: 10.1002/ehf2.13922
Abstract: AIM We present the baseline characteristics of the PREFERS Stockholm epidemiological study on the natural history and course of new onset heart failure (HF) aiming to improve phenotyping focusing on HF with preserved left ventricular… read more here.
Keywords: heart; hfpef; new onset; hfref ... See more keywords
Heart failure with reduced ejection fraction and atrial fibrillation: a Sub‐Saharan African perspective
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DOI: 10.1002/ehf2.14332
Abstract: Cardiovascular diseases are a well‐established cause of death in high‐income countries. In the last 20 years, Sub‐Saharan Africa (SSA) has seen one of the sharpest increases in cardiovascular disease‐related mortality, superseding that of infectious diseases,… read more here.
Keywords: heart failure; heart; atrial fibrillation; hfref ... See more keywords
Are the effects of drugs to prevent and to treat heart failure always concordant? The statin paradox and its implications for understanding the actions of antidiabetic medications
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DOI: 10.1002/ejhf.1183
Abstract: Most treatments for chronic heart failure are effective both in preventing its onset and reducing its progression. However, statins prevent the development of heart failure, but they do not decrease morbidity and mortality in those… read more here.
Keywords: heart; effects drugs; implications understanding; heart failure ... See more keywords
Gut dysbiosis and heart failure: navigating the universe within
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DOI: 10.1002/ejhf.1792
Abstract: Alternations in gut microbial composition (i.e. loss of microbial diversity or ‘gut dysbiosis’) have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low‐level inflammation and… read more here.
Keywords: dysbiosis; gut dysbiosis; heart failure; gut microbial ... See more keywords
Device therapy in heart failure with reduced ejection fraction—cardiac resynchronization therapy and more
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DOI: 10.1007/s00059-018-4710-6
Abstract: In patients with heart failure with reduced ejection fraction (HFrEF), optimal medical treatment includes beta-blockers, ACE inhibitors/angiotensinreceptor-neprilysin inhibitors (ARNI), mineralocorticoid receptor antagonists, and ivabradine when indicated. In device therapy of HFrEF, implantable cardioverter-defibrillators and cardiac… read more here.
Keywords: therapy; hfref; die; heart failure ... See more keywords
Evaluating the Safety and Tolerability of Sacubitril/Valsartan for HFrEF Managed Within a Pharmacist Clinic
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DOI: 10.1007/s40256-018-0264-5
Abstract: ObjectiveThe objective of this research was to describe the use of pharmacist-managed sacubitril/valsartan therapy in a multi-center, outpatient cardiac group.BackgroundSacubitril/valsartan, an angiotensin receptor-neprilysin inhibitor (ARNi), is a novel agent for the treatment of heart failure.… read more here.
Keywords: within pharmacist; sacubitril valsartan; hfref; therapy ... See more keywords
Mortality in Patients with Heart Failure With Recovered Ejection Fraction - Outcomes From an Urban Teaching Medical Center.
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DOI: 10.1016/j.cardfail.2018.07.294
Abstract: Background Heart failure with recovered ejection fraction (HFrecEF) is a newly emerged subset of patients who previously had reduced ejection fraction (HFrEF), but had improvement or recovery by natural history or in response to therapy.… read more here.
Keywords: ejection fraction; failure; hfref; study ... See more keywords
Phenotyping congestion in patients with acutely decompensated heart failure with preserved and reduced ejection fraction: The Decongestion duRing therapY for acute decOmpensated heart failure in HFpEF vs HFrEF- DRY-OFF study.
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DOI: 10.1016/j.ejim.2021.11.010
Abstract: AIMS To evaluate pulmonary and intravascular congestion at admission and repeatedly during hospitalization for acute decompensated heart failure (ADHF) in HFrEF and HFpEF patients using lung (LUS) and inferior vena cava (IVC) ultrasound. METHODS AND… read more here.
Keywords: decompensated heart; heart failure; congestion; hfref ... See more keywords
Transcatheter mitral valve repair may increase eligibility for heart transplant listing in patients with end-stage heart failure and severe secondary mitral regurgitation.
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DOI: 10.1016/j.ijcard.2021.06.031
Abstract: BACKGROUND Heart transplantation remains the gold standard for treatment of patients with end-stage heart failure and severely reduced ejection fraction (HFrEF). An increased pulmonary vascular resistance (PVR), which is often prevalent in HFrEF patients with… read more here.
Keywords: heart; eligibility; transplantation; hfref ... See more keywords
Sodium-glucose co-transporter-2 inhibitors eligibility in patients with heart failure with reduced ejection fraction.
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DOI: 10.1016/j.ijcard.2021.08.035
Abstract: BACKGROUND The sodium-glucose co-transporter-2 (SGLT2) inhibitors dapagliflozin and empagliflozin have been demonstrated to reduce adverse cardiovascular outcomes in patients with heart failure with reduced ejection fraction (HFrEF). Limited data are available characterizing the generalizability of… read more here.
Keywords: sglt2 inhibitors; sodium glucose; glucose transporter; eligibility ... See more keywords
WORSENING RENAL FUNCTION, HYPERKALEMIA AND HYPOTENSION IN SACUBITRIL-VALSARTAN VS. ENALAPRIL IN HFREF: A META-ANALYSIS
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DOI: 10.1016/s0735-1097(20)31595-3
Abstract: Sacubitril-valsartan has shown significant promise in patients with Heart Failure with reduced Ejection Fraction (HFrEF). We compared the safety of the sacubitril-valsartan with enalapril in patients with HFrEF. A comprehensive search was performed on PubMed,… read more here.
Keywords: sacubitril; sacubitril valsartan; valsartan enalapril; worsening renal ... See more keywords