Protective Effects of Syringic Acid Against Oxidative Damage, Apoptosis, Autophagy, Inflammation, Testicular Histopathologic Disorders, and Impaired Sperm Quality in the Testicular Tissue of Rats Induced by Mercuric Chloride
Sign Up to like & getrecommendations! Published in 2024 at "Environmental Toxicology"
DOI: 10.1002/tox.24395
Abstract: Mercury (Hg) is one of the most toxic heavy metals that damage testicular tissue. Mercury chloride (HgCl2) is one of the most toxic forms of mercury that can easily cross biological membranes. Syringic acid (SA)… read more here.
Keywords: testicular tissue; damage; hgcl2; inflammation ... See more keywords
Protective Effects of Carvacrol on Mercuric Chloride‐Induced Lung Toxicity Through Modulating Oxidative Stress, Apoptosis, Inflammation, and Autophagy
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DOI: 10.1002/tox.24397
Abstract: Mercuric chloride (HgCl2) is extremely toxic to both humans and animals. It could be absorbed via ingestion, inhalation, and skin contact. Exposure to HgCl2 can cause severe health effects, including damages to the gastrointestinal, respiratory,… read more here.
Keywords: oxidative stress; inflammation autophagy; crv; hgcl2 ... See more keywords
Mercury chloride toxicity in human erythrocytes: enhanced generation of ROS and RNS, hemoglobin oxidation, impaired antioxidant power, and inhibition of plasma membrane redox system
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-018-04062-5
Abstract: Mercury is among the most toxic heavy metals and a widespread environmental pollutant. Mercury chloride (HgCl2) is an inorganic compound of mercury which is easily absorbed in the gastrointestinal tract and then enters the blood… read more here.
Keywords: hemoglobin oxidation; mercury chloride; hgcl2; human erythrocytes ... See more keywords
Ziziphus spina-christi leaf extract attenuates mercury chloride-induced testicular dysfunction in rats
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-07237-w
Abstract: Mercury (Hg) is a heavy metal toxicant, causing several adverse reactions to animals and humans including reproductive dysfunction. The potential protective role of Ziziphus spina-christi leaf extract (ZSCLE) against testicular impairments associated with mercury chloride… read more here.
Keywords: dysfunction; leaf extract; ziziphus spina; christi leaf ... See more keywords
Leaf ethanolic extract of Etlingera hemesphaerica Blume alters mercuric chloride teratogenicity during the post-implantation period in Mus musculus.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicological research"
DOI: 10.1007/s43188-019-00010-8
Abstract: This study aimed to investigate the effectiveness of leaf ethanolic extract of Etlingera hemisphaerica (LE3H) against the teratogenic effects of mercuric chloride (HgCl2) in mice (Mus musculus). Pregnant M. musculus were divided into four groups,… read more here.
Keywords: teratogenicity; ethanolic extract; mercuric chloride; hgcl2 ... See more keywords
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity.
Sign Up to like & getrecommendations! Published in 2020 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.110801
Abstract: Mercury (Hg) pollution poses global human health and environmental risks. However, still knowledge gaps exist on both exposures and health effects. Here, we combined transcriptome sequencing technique to further investigate the specific mechanisms of inorganic… read more here.
Keywords: induced nephrotoxicity; ppar agonist; translocation; hgcl2 ... See more keywords
Changes in the renal function after acute mercuric chloride exposure in the rat are associated with renal vascular endothelial dysfunction and proximal tubule NHE3 inhibition.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2021.01.014
Abstract: Mercury is an environmental pollutant and a threat to human health. Mercuric chloride (HgCl2)-induced acute renal failure has been described by several reports, but the mechanisms of renal dysfunction remain elusive. This study tested the… read more here.
Keywords: mercuric chloride; renal vascular; inhibition; proximal tubule ... See more keywords
Thymoquinone Induces Nrf2 Mediated Adaptive Homeostasis: Implication for Mercuric Chloride-Induced Nephrotoxicity
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DOI: 10.1021/acsomega.2c00028
Abstract: Background: the primary function of the kidney is to eliminate metabolic waste products and xenobiotics from the circulation. During this process, the kidney may become vulnerable to toxicity. Objective: it was aimed to investigate the… read more here.
Keywords: induced nephrotoxicity; hgcl2; expression; thymoquinone ... See more keywords
Enhanced Activity in the Tosylation of Tolanophanes via Supramolecular HgCl2 Recognition
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DOI: 10.1071/ch18376
Abstract: The ‘self-activation’ of host molecules via the incorporation of a guest has received considerable attention in supramolecular catalysis. Here, we demonstrate how HgCl2 effects the tosylation rate of tolanophanes (1a–c: n = 2−4) with different alkyl chain… read more here.
Keywords: tosylation; tosylation tolanophanes; enhanced activity; hgcl2 ... See more keywords
Changes in intraepidermal nerve fiber and Langerhans cell densities in the plantar skin of rats after mercuric chloride exposure
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Peripheral Nervous System"
DOI: 10.1111/jns.12246
Abstract: Mercury and its compounds possess strong neurotoxicity and patients with mercury poisoning often report pain and numbness in the distal extremities that conform to the “stocking–glove” pattern. However, no study has investigated whether damage to… read more here.
Keywords: plantar skin; intraepidermal nerve; skin rats; hgcl2 ... See more keywords
Protective effect of Moringa oleifera oil against HgCl2-induced hepato- and nephro-toxicity in rats
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DOI: 10.1515/jbcpp-2016-0033
Abstract: Abstract: Background: Various parts of the Moringa oleifera (M. oleifera) tree are widely accepted to have ameliorative effects against metal toxicity. In the present study, M. oleifeira oil (MO) was tested against HgCl2-induced tissue pathologies… read more here.
Keywords: moringa oleifera; group; hgcl2 group; hgcl2 ... See more keywords