Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-019-0354-0
Abstract: Alkaptonuria (AKU) is a rare metabolic disorder caused by a deficient enzyme in the tyrosine degradation pathway, homogentisate 1,2-dioxygenase (HGD). In 172 AKU patients from 39 countries, we identified 28 novel variants of the HGD… read more here.
Keywords: genotype phenotype; hgd; homogentisate dioxygenase; dioxygenase hgd ... See more keywords
Endoscopic resection is feasible for high-grade dysplasia in patients with ulcerative colitis
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2022.2107878
Abstract: Abstract Background Endoscopic resection (ER) is feasible for treating well-circumscribed dysplasia in patients with ulcerative colitis (UC). However, long-term prognosis of ER for high-grade dysplasia (HGD) in patients with UC remains unclear. We aimed to… read more here.
Keywords: dysplasia; hgd; grade dysplasia; endoscopic resection ... See more keywords
Adequacy in Endocervical Curettage.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqac058
Abstract: OBJECTIVES Specimen adequacy is an important quality assurance component of a cervical Papanicolaou test. Although consensus exists on minimal acceptable cellularity for cervical Papanicolaou tests, no such criteria exist for endocervical curettage (ECC) specimens. We… read more here.
Keywords: ecc; endocervical curettage; ihc; ecc specimens ... See more keywords
Racial Disparity in the Sex Distribution, the Prevalence, and the Incidence of Dysplasia in Barrett’s Esophagus
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000000559
Abstract: Goals: Our aim was to study the prevalence of dysplasia and progression to high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) in African Americans (AA) with Barrett’s esophagus (BE) and compare it with that of non-Hispanic… read more here.
Keywords: barrett esophagus; hgd; eac; prevalence ... See more keywords
The potential diagnostic significance of crypt differentiation in gastric dysplasia.
Sign Up to like & getrecommendations! Published in 2021 at "Histopathology"
DOI: 10.1111/his.14581
Abstract: AIMS This study investigated the relationship between the differentiation of tumour cells into crypts, which is determined by cell differentiation into Paneth and neuroendocrine cells, and tumour infiltration in gastric dysplasia. METHODS AND RESULTS The… read more here.
Keywords: hgd; without crypt; differentiation; dysplasia ... See more keywords
PTH-007 Real world experience with rfa/emr in early oesophageal neoplasia
Sign Up to like & getrecommendations! Published in 2017 at "Gut"
DOI: 10.1136/gutjnl-2017-314472.404
Abstract: Introduction Endoscopic resection and ablation treatment is the standard of care for barretts oesophagus and related early neoplasia. To evaluate the real world experience with EMR and RFA treatment at a single centre outside of… read more here.
Keywords: rfa emr; real world; hgd; rfa ... See more keywords
Comparison of Clinical and Imaginal Features According to the Pathological Grades of Dysplasia in Branch-Duct Intraductal Papillary Mucinous Neoplasm (BD-IPMN) for Personalized Medicine
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13010149
Abstract: Background: In patients with BD-IPMN, surgical indications have been focused on finding malignant lesions (HGD, high-grade dysplasia/IC, invasive carcinoma). The aim of this study was to compare the preoperative factors that distinguish HGD from LGD… read more here.
Keywords: pathologic target; surgery; personalized medicine; optimal pathologic ... See more keywords