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   Articles with "hgg" as a keyword



Splicing is an alternate oncogenic pathway activation mechanism in glioma

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recommendations! Published in 2022 at "Nature Communications"

DOI: 10.1038/s41467-022-28253-4

Abstract: High-grade diffuse glioma (HGG) is the leading cause of brain tumour death. While the genetic drivers of HGG have been well described, targeting these has thus far had little impact on survival suggesting other mechanisms… read more here.

Keywords: cancer; hgg; glioma; pathway ... See more keywords

Immunoglobulin G dynamics and outcomes of hypogammaglobulinemia in liver transplant recipients

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-16543-y

Abstract: Hypogammaglobulinemia (HGG) is a common complication of liver transplantation (LT). However, the impact of underlying liver disease severity on post-LT immunoglobulin dynamics remains unclear. We aimed to evaluate the differences in serum immunoglobulin G (IgG)… read more here.

Keywords: outcomes hypogammaglobulinemia; hgg; immunoglobulin dynamics; hypogammaglobulinemia liver ... See more keywords
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HGG-17. HIGH-GRADE GLIOMA IN VERY YOUNG CHILDREN; A SINGLE-CENTER 11-YEAR-EXPERIENCE

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recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.304

Abstract: Abstract BACKGROUND Data about high-grade glioma (HGG) in very young children (≤3 years old at diagnosis) is scarce. METHODS 180 pediatric HGG patients were treated at the Children Cancer Hospital - Egypt (CCHE-57357) between July… read more here.

Keywords: grade glioma; high grade; year; hgg ... See more keywords

HGG-58. SIOPE HGG Working Group approach to obtain consensus on management of paediatric high grade glioma across Europe

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recommendations! Published in 2022 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noac079.273

Abstract: Abstract BACKGROUND: There is currently no European standard clinical practice on the management of paediatric HGG (pHGG). AIMS: To develop approved clinical recommendations for the management of pHGG reflecting current best practice, with the ultimate… read more here.

Keywords: management paediatric; consensus; hgg; across europe ... See more keywords

The development of a rapid patient-derive d xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors.

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recommendations! Published in 2023 at "Neuro-oncology"

DOI: 10.1093/neuonc/noad047

Abstract: BACKGROUND High-grade gliomas (HGG) are aggressive brain tumors associated with short median patient survival and limited response to therapies, driving the need to develop tools to improve patient outcomes. Patient-derived xenograft (PDX) models, such as… read more here.

Keywords: oncology; hgg; xenograft; patient ... See more keywords

HGG-27.IDH- AND H3-WILDTYPE HIGH-GRADE GLIOMAS OCCURRING IN TEENAGERS AND YOUNG ADULT PATIENTS COMPRISE NOVEL MOLECULAR SUBGROUPS

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recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae064.311

Abstract: Abstract BACKGROUND High-grade gliomas (HGG) arise in any CNS location with a poor prognosis. HGGs in teenagers/young adults (TYA) are understudied; this project aimed to characterise these tumours and identify therapeutic targets. METHODS HGG samples… read more here.

Keywords: methylation; idh wildtype; high grade; teenagers young ... See more keywords

HGG-43. DIFFUSE PEDIATRIC HIGH GRADE GLIOMA SUCCESSFULLY TREATED WITH MULTIMODAL THERAPY

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recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae064.327

Abstract: Abstract BACKGROUND Pediatric high grade glioma (HGG) have a dismal prognosis despite aggressive treatment. In this report, we discuss a patient with HGG successfully treated with combination of resection, radiotherapy, chemotherapy, and biologic therapy. RESULTS… read more here.

Keywords: grade glioma; therapy; high grade; hgg ... See more keywords

HGG-49. INTERNEURONS THAT BITE: A CELLULAR DELIVERY SYSTEM FOR PEDIATRIC HIGH-GRADE GLIOMA

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recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae064.333

Abstract: Abstract BACKGROUND High-grade gliomas (HGG) represent the leading cause of cancer-related mortality in children due to a lack of curative therapies. Challenges of cellular therapies in brain tumors include the lack of unique tumor antigens,… read more here.

Keywords: high grade; cellular delivery; delivery system; hgg ... See more keywords

P17.10.B RETROSPECTIVE ANALYSIS OF RADIOCHEMOTHERAPY WITH CONCURRENT OR SEQUENTIAL TUMOR-TREATING FIELDS (TTFIELDS) IN PATIENTS WITH HIGH-GRADE GLIOMA (HGG) IN CHINA.

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf193.526

Abstract: High-grade gliomas (HGG) are aggressive primary Central Nervous System(CNS)tumors with poor survival outcomes and limited treatment options. Tumor-treating fields (TTFields) therapy, using low-intensity electric fields, has shown promise when combined with radiochemotherapy (CRT). The EF-14… read more here.

Keywords: ttf group; high grade; tumor treating; group ... See more keywords

IMG-11. GUARD-HGG: An AI-driven decision system for personalized radiochemotherapy recommendation in high-grade glioma

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recommendations! Published in 2025 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaf201.1090

Abstract: We developed and validated a machine learning-based system, GUARD-HGG, to non-invasively predict radiochemotherapy (RCT) sensitivity in patients with high-grade glioma (HGG), with the goal of supporting personalized RCT recommendations. A retrospective training set of 1,221… read more here.

Keywords: hospital; grade glioma; high grade; hgg ... See more keywords

P04.09 Low-grade and high-grade glioma patients show different remote effects of the brain tumor on the functional network topology of the contralesional hemisphere

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recommendations! Published in 2017 at "Neuro-oncology"

DOI: 10.1093/neuonc/nox036.149

Abstract: Introduction: Patients with unilateral brain tumors show dramatic alterations in functional brain connectivity. These alterations are not only restricted to the tumor area, but are also thought to occur in remote, even contralateral areas. Functional… read more here.

Keywords: functional network; network; grade; hgg ... See more keywords