Splicing is an alternate oncogenic pathway activation mechanism in glioma
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28253-4
Abstract: High-grade diffuse glioma (HGG) is the leading cause of brain tumour death. While the genetic drivers of HGG have been well described, targeting these has thus far had little impact on survival suggesting other mechanisms… read more here.
Keywords: cancer; hgg; glioma; pathway ... See more keywords
HGG-17. HIGH-GRADE GLIOMA IN VERY YOUNG CHILDREN; A SINGLE-CENTER 11-YEAR-EXPERIENCE
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.304
Abstract: Abstract BACKGROUND Data about high-grade glioma (HGG) in very young children (≤3 years old at diagnosis) is scarce. METHODS 180 pediatric HGG patients were treated at the Children Cancer Hospital - Egypt (CCHE-57357) between July… read more here.
Keywords: grade glioma; high grade; year; hgg ... See more keywords
HGG-58. SIOPE HGG Working Group approach to obtain consensus on management of paediatric high grade glioma across Europe
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noac079.273
Abstract: Abstract BACKGROUND: There is currently no European standard clinical practice on the management of paediatric HGG (pHGG). AIMS: To develop approved clinical recommendations for the management of pHGG reflecting current best practice, with the ultimate… read more here.
Keywords: management paediatric; consensus; hgg; across europe ... See more keywords
The development of a rapid patient-derive d xenograft model to predict chemotherapeutic drug sensitivity/resistance in malignant glial tumors.
Sign Up to like & getrecommendations! Published in 2023 at "Neuro-oncology"
DOI: 10.1093/neuonc/noad047
Abstract: BACKGROUND High-grade gliomas (HGG) are aggressive brain tumors associated with short median patient survival and limited response to therapies, driving the need to develop tools to improve patient outcomes. Patient-derived xenograft (PDX) models, such as… read more here.
Keywords: oncology; hgg; xenograft; patient ... See more keywords
P04.09 Low-grade and high-grade glioma patients show different remote effects of the brain tumor on the functional network topology of the contralesional hemisphere
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-oncology"
DOI: 10.1093/neuonc/nox036.149
Abstract: Introduction: Patients with unilateral brain tumors show dramatic alterations in functional brain connectivity. These alterations are not only restricted to the tumor area, but are also thought to occur in remote, even contralateral areas. Functional… read more here.
Keywords: functional network; network; grade; hgg ... See more keywords
An evidence-based approach to assess the accuracy of intravoxel incoherent motion imaging for the grading of brain tumors
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013217
Abstract: Background: Differentiation of high-grade gliomas (HGGs) and low-grade gliomas (LGGs) is an important clinical problem because treatment strategies vary greatly. This study was performed to investigate the potential diagnostic value of incoherent intravoxel motion imaging… read more here.
Keywords: hgg; hgg lgg; motion imaging; value ... See more keywords
Solving Robotic Manipulation With Sparse Reward Reinforcement Learning Via Graph-Based Diversity and Proximity
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Industrial Electronics"
DOI: 10.1109/tie.2022.3172754
Abstract: In multigoal reinforcement learning (RL), algorithms usually suffer from inefficiency in the collection of successful experiences in tasks with sparse rewards. By utilizing the ideas of relabeling hindsight experience and curriculum learning, some prior works… read more here.
Keywords: reinforcement learning; hgg; robotic manipulation; graph based ... See more keywords
Intravenous Immunoglobulin in Heart Transplant Recipients with Mild to Moderate Hypogammaglobulinemia and Infection.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical transplantation"
DOI: 10.1111/ctr.14571
Abstract: BACKGROUND Hypogammaglobulinemia (HGG) is a complication of solid organ transplantation leading to increased risk of infections. Intravenous immunoglobulin G (IVIG) replacement in patients with HGG may be able to reduce risk and morbidity associated with… read more here.
Keywords: heart transplant; hgg; transplant recipients; infection ... See more keywords
Abstract 2234: m6A RNA methylation as a therapeutic target in high grade glioma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2234
Abstract: Background: High grade glioma (HGG) is a devastating brain cancer with median survival of less than 18 months. The field of epitranscriptomics has emerged as a novel druggable target for multiple diseases, including cancers, with… read more here.
Keywords: m6a rna; m6a; rna methylation; hgg ... See more keywords
Clonal Evolution of a High-Grade Pediatric Glioma With Distant Metastatic Spread
Sign Up to like & getrecommendations! Published in 2021 at "Neurology: Genetics"
DOI: 10.1212/nxg.0000000000000561
Abstract: Objective High-grade glioma (HGG) rarely spreads outside the CNS. To test the hypothesis that the lesions were metastases originating from an HGG, we sequenced the relapsing HGG and distant extraneural lesions. Methods We performed whole-exome… read more here.
Keywords: high grade; glioma; outside cns; spread ... See more keywords
Intraoperative shear-wave elastography and superb microvascular imaging contribute to the glioma grading
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Neuroscience"
DOI: 10.2139/ssrn.4308332
Abstract: BACKGROUND To explore the diagnostic value and feasibility of shear wave elastography and superb microvascular imaging in the grading diagnosis of glioma intraoperatively. MATERIALS AND METHODS Forty-nine patients with glioma were included in this study.… read more here.
Keywords: hgg; shear wave; superb microvascular; microvascular imaging ... See more keywords