Combination treatment with growth hormone and zoledronic acid in a mouse model of Osteogenesis imperfecta.
Sign Up to like & getrecommendations! Published in 2022 at "Bone"
DOI: 10.1016/j.bone.2022.116378
Abstract: INTRODUCTION Osteogenesis imperfecta (OI) or brittle bone disease is a genetic disorder that results in bone fragility. Bisphosphonates such as zoledronic acid (ZA) are used clinically to increase bone mass and reduce fracture risk. Human… read more here.
Keywords: bone; combination; osteogenesis imperfecta; treatment ... See more keywords
The Effect of Human Growth Hormone Treatment on the Development of Slipped Capital Femoral Epiphysis: A Cohort Analysis With 6 Years of Follow-up
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Pediatric Orthopaedics"
DOI: 10.1097/bpo.0000000000002618
Abstract: Background: Slipped capital femoral epiphysis (SCFE) is a common hip disorder in adolescents that can result in substantial complications, impacting the quality of life. Human Growth Hormone (HGH) administration may elevate the risk of SCFE,… read more here.
Keywords: cohort; hgh; capital femoral; scfe ... See more keywords
Can Human Growth Hormone Accelerate Tendon and Ligament Injury Recovery?
Sign Up to like & getrecommendations! Published in 2024 at "Sports Health"
DOI: 10.1177/19417381241245938
Abstract: Background: Studies involving human fibroblasts and use of human growth hormone (HGH) administration for injury recovery are limited. It is plausible that if the administration of HGH to human cells increased cellular proliferation and differentiation,… read more here.
Keywords: hgh; tendon ligament; recovery; injury ... See more keywords
Improvement of treatment adherence with growth hormone by easypod™ device: experience of an Italian centre
Sign Up to like & getrecommendations! Published in 2018 at "Italian Journal of Pediatrics"
DOI: 10.1186/s13052-018-0548-z
Abstract: BackgroundOne of the most important vulnerabilities falling the efficacy of recombinant human growth hormone (r-hGH) treatment is low adherence especially in young patients. This study was planned to describe the correlation between r-hGH treatment efficacy… read more here.
Keywords: treatment; treatment adherence; growth hormone; hgh ... See more keywords
The Unfolding Story of Protein Misfolding Causing Alzheimer Disease in Recipients of Human Pituitary Growth Hormone
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvaf029
Abstract: Abstract Human growth hormone (hGH) has been in clinical use for children with GH deficiency (GHD) since the late 1950s. The original formulations were considered very safe with few adverse events reported. That changed remarkably… read more here.
Keywords: alzheimer disease; disease; growth hormone; hgh ... See more keywords
Amino acid substitutions in human growth hormone affect secondary structure and receptor binding
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DOI: 10.1371/journal.pone.0282741
Abstract: The interaction between human Growth Hormone (hGH) and hGH Receptor (hGHR) has basic relevance to cancer and growth disorders, and hGH is the scaffold for Pegvisomant, an anti-acromegaly therapeutic. For the latter reason, hGH has… read more here.
Keywords: hgh; hghr; growth; growth hormone ... See more keywords
Weight loss-independent changes in human growth hormone during water-only fasting: a secondary evaluation of a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2024.1401780
Abstract: Introduction: Water-only fasting for one day or more may provide health benefits independent of weight loss. Human growth hormone (HGH) may play a key role in multiple fasting-triggered mechanisms. Whether HGH changes during fasting are… read more here.
Keywords: weight loss; water fasting; hgh; human growth ... See more keywords
Autocrine Human Growth Hormone Promotes Invasive and Cancer Stem Cell-Like Behavior of Hepatocellular Carcinoma Cells by STAT3 Dependent Inhibition of CLAUDIN-1 Expression
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18061274
Abstract: Despite progress in diagnosis and treatment of hepatocellular carcinoma (HCC), the clinical outcome is still unsatisfactory. Increased expression of human growth hormone (hGH) in HCC has been reported and is associated with poor survival outcome… read more here.
Keywords: hcc; claudin; expression; forced expression ... See more keywords
Topical Delivery of Cell-Penetrating Peptide-Modified Human Growth Hormone for Enhanced Wound Healing
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DOI: 10.3390/ph16030394
Abstract: Protein drugs have been emerging as a class of promising therapeutics. However, their topical application has been limited by their high molecular weight and poor permeability to the cell membrane. In this study, we aimed… read more here.
Keywords: hgh; cell; wound healing; tat hgh ... See more keywords
Alteration in cardiac PI3K/Akt/mTOR and ERK signaling pathways with the use of growth hormone and swimming, and the roles of miR21 and miR133
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical Reports"
DOI: 10.3892/br.2018.1179
Abstract: Athletes misuse recombinant human growth hormone (r-hGH) to enhance their performance. Although r-hGH is known to increase cardiac hypertrophy, the underlying molecular mechanism remains unclear. The aim of the present study was to investigate the… read more here.
Keywords: growth hormone; pi3k; expression; hgh ... See more keywords