Experimental study on post-fire performance of half grouted sleeve connection with construction defect
Sign Up to like & getrecommendations! Published in 2020 at "Construction and Building Materials"
DOI: 10.1016/j.conbuildmat.2020.118165
Abstract: Abstract Half grouted sleeve connection (HGSC) is widely used in joining rebars in precast concrete structures. Construction defects and fires are inevitable in practical projects. However, the mechanical behaviors of post-fire HGSC with construction defect… read more here.
Keywords: construction; hgsc; construction defect; post fire ... See more keywords
Differential expression of immune related genes in high-grade ovarian serous carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2019.12.019
Abstract: OBJECTIVE To identify novel immunologic targets and biomarkers associated with overall survival (OS) in high-grade serous ovarian cancer (HGSC). METHODS In this retrospective study, microarray data from 51 HGSC specimens were analyzed (Affymetrix HG-U133A). A… read more here.
Keywords: high grade; expression; related genes; hgsc ... See more keywords
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-88382-6
Abstract: Erythropoietin producing hepatocellular (Eph) receptors and their membrane-bound ligands ephrins are variably expressed in epithelial cancers, with context-dependent implications to both tumor-promoting and -suppressive processes in ways that remain incompletely understood. Using ovarian cancer tissue… read more here.
Keywords: epha2; aggressive recurrent; ovarian cancers; recurrent ovarian ... See more keywords
A combination of molecular and clinical parameters provides a new strategy for high-grade serous ovarian cancer patient management
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Translational Medicine"
DOI: 10.1136/ijgc-2022-esgo.897
Abstract: Background High-grade serous carcinoma (HGSC) is the most common and deadly subtype of ovarian cancer. Although most patients will initially respond to first-line treatment with a combination of surgery and platinum-based chemotherapy, up to a… read more here.
Keywords: new strategy; hgsc; patient; strategy ... See more keywords
Long-term tumour dormancy in a BRCA1 heterozygote
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2021-108269
Abstract: Ovarian highgrade serous carcinoma (HGSC) is thought to mainly arise from the Fallopian tubes from a precursor lesion known as serous tubal intraepithelial carcinoma (STIC). 2 Germline pathogenic variants (GPVs) in BRCA1/2 are the most… read more here.
Keywords: brca1; hgsc; rrso; tumour ... See more keywords
Abstract 3984: NB compound FOXM1 inhibitors have potent anti-cancer activity in high-grade serous ovarian carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3984
Abstract: Introduction: High-grade serous ovarian carcinoma (HGSC) is characterized by frequent overexpression and activation of the Forkhead Box M1 (FOXM1) transcription factor, suggesting it as a therapeutic target. This study focused on characterizing the activity of… read more here.
Keywords: compound; hgsc; hgsc cells; foxm1 inhibitors ... See more keywords
Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Research"
DOI: 10.1158/1541-7786.mcr-18-1233
Abstract: Epithelial ovarian cancer (EOC) is the deadliest gynecologic cancer. High-grade serous carcinoma (HGSC) is the most frequently diagnosed and lethal histosubtype of EOC. A significant proportion of patients with HGSC relapse with chemoresistant disease. Therefore,… read more here.
Keywords: high grade; therapy; ovarian cancer; cancer ... See more keywords
Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal for Immunotherapy of Cancer"
DOI: 10.1186/s40425-019-0781-z
Abstract: BackgroundAdjuvanticity, which is the ability of neoplastic cells to deliver danger signals, is critical for the host immune system to mount spontaneous and therapy-driven anticancer immune responses. One of such signals, i.e., the exposure of… read more here.
Keywords: prognosis; immune responses; exposure; primary metastatic ... See more keywords
Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0255007
Abstract: Ovarian high grade serous carcinoma (HGSC) is a lethal form of ovarian cancer (OVCA). In most cases it is detected at late stages as the symptoms are non-specific during early stages. Emerging information suggests that… read more here.
Keywords: ovarian hgsc; oviductal fimbria; preclinical model; hgsc ... See more keywords
Long Non-Coding RNA MAGI2-AS3 is a New Player with a Tumor Suppressive Role in High Grade Serous Ovarian Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11122008
Abstract: High-Grade Serous Ovarian Carcinoma (HGSC) is the most incidental and lethal subtype of epithelial ovarian cancer (EOC) with a high mortality rate of nearly 65%. Recent findings aimed at understanding the pathogenesis of HGSC have… read more here.
Keywords: high grade; non coding; role; hgsc ... See more keywords
Characterization of Primary Mucinous Ovarian Cancer by Diffusion-Weighted and Dynamic Contrast Enhancement MRI in Comparison with Serous Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15051453
Abstract: Simple Summary Epithelial ovarian cancer (EOC) has always been considered one of the most challenging problems for gynecologic oncologists. This is not only due to difficulties in treatment, but also in the diagnosis and differentiation… read more here.
Keywords: diffusion; hgsc; contrast; ovarian cancer ... See more keywords